Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.006 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0822 | 0.0822 |
Onchocerca volvulus | 0.001 | 0.0822 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0043 | 0.6965 | 0.6965 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0043 | 0.6965 | 0.6965 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0822 | 0.0822 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0822 | 0.0822 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0822 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.006 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0043 | 0.6965 | 0.6965 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | TAR-binding protein | 0.006 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0822 | 0.0822 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | RNA recognition motif domain containing protein | 0.006 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0043 | 0.6965 | 0.6965 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | tar DNA binding protein | 0.006 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0043 | 0.6965 | 0.6965 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0043 | 0.6965 | 0.6965 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0822 | 0.0822 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0043 | 0.6965 | 0.6965 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0822 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0043 | 0.6965 | 0.6965 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0822 | 0.0822 |
Echinococcus multilocularis | tar DNA binding protein | 0.006 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | TAR-binding protein | 0.006 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0822 | 0.0822 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0822 | 0.0822 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0822 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0822 | 0.0822 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0043 | 0.6965 | 0.6965 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0822 | 0.0822 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0822 | 0.0822 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.