Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0879 | 0.1209 | 0.1142 |
Trichomonas vaginalis | AGC family protein kinase | 0.2807 | 0.5061 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0879 | 0.1209 | 0.2388 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.18 | 0.305 | 0.3167 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.2807 | 0.5061 | 0.5251 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2807 | 0.5061 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.2807 | 0.5061 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.18 | 0.305 | 0.3091 |
Trichomonas vaginalis | AGC family protein kinase | 0.2807 | 0.5061 | 0.5 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.2807 | 0.5061 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.2807 | 0.5061 | 0.5 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.2807 | 0.5061 | 1 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.2807 | 0.5061 | 0.538 |
Echinococcus granulosus | hypothetical protein | 0.502 | 0.9484 | 1 |
Echinococcus multilocularis | conserved hypothetical protein | 0.4908 | 0.9261 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.036 | 0.0171 | 0.0338 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0879 | 0.1209 | 0.1114 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 0 % | Compound was tested for inhibition of Adenovirus type 2 proteinase; showed no inhibitory activity | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.