Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Aurora kinase | 0.0127 | 0.0339 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0127 | 0.0339 | 0.5 |
Onchocerca volvulus | 0.0153 | 0.0552 | 0.5 | |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0792 | 0.5771 | 1 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0127 | 0.0339 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0127 | 0.0339 | 0.0587 |
Loa Loa (eye worm) | AUR protein kinase | 0.0127 | 0.0339 | 0.0587 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0192 | 0.0868 | 0.2937 |
Entamoeba histolytica | protein kinase , putative | 0.0127 | 0.0339 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.0552 | 0.0803 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0192 | 0.0868 | 0.2937 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0153 | 0.0552 | 0.0957 |
Toxoplasma gondii | aurora kinase | 0.0127 | 0.0339 | 1 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0792 | 0.5771 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Entamoeba histolytica | protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0127 | 0.0339 | 0.0339 |
Trypanosoma brucei | aurora B kinase | 0.0127 | 0.0339 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Echinococcus multilocularis | aurora kinase A | 0.0127 | 0.0339 | 0.0339 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0127 | 0.0339 | 0.0587 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.0552 | 0.0803 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0153 | 0.0552 | 0.0552 |
Brugia malayi | serine/threonine kinase 12 | 0.0127 | 0.0339 | 0.0587 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0153 | 0.0552 | 0.0552 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0127 | 0.0339 | 0.5 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0127 | 0.0339 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0153 | 0.0552 | 0.0552 |
Schistosoma mansoni | protein kinase | 0.0127 | 0.0339 | 0.0427 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqI | 0.0192 | 0.0868 | 0.5 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0127 | 0.0339 | 0.0587 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0192 | 0.0868 | 0.2937 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0097 | 0.0167 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0348 | 0.214 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0127 | 0.0339 | 0.0339 |
Leishmania major | protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0792 | 0.5771 | 1 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0127 | 0.0339 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0127 | 0.0339 | 0.5 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQI | 0.0192 | 0.0868 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0153 | 0.0552 | 0.0957 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.131 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0127 | 0.0339 | 0.0427 |
Loa Loa (eye worm) | AUR protein kinase | 0.0127 | 0.0339 | 0.0587 |
Echinococcus granulosus | aurora kinase A | 0.0127 | 0.0339 | 0.0339 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0348 | 0.214 | 1 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.131 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.