Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | serine/threonine kinase 12 | 0.0127 | 0.0339 | 0.0587 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0153 | 0.0552 | 0.0552 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0153 | 0.0552 | 0.0552 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0127 | 0.0339 | 0.0587 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.0552 | 0.0803 |
Echinococcus multilocularis | aurora kinase A | 0.0127 | 0.0339 | 0.0339 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0127 | 0.0339 | 0.0339 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Trypanosoma brucei | aurora B kinase | 0.0127 | 0.0339 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Toxoplasma gondii | aurora kinase | 0.0127 | 0.0339 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0153 | 0.0552 | 0.0957 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0792 | 0.5771 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.0552 | 0.0803 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0192 | 0.0868 | 0.2937 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0192 | 0.0868 | 0.2937 |
Entamoeba histolytica | protein kinase , putative | 0.0127 | 0.0339 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0127 | 0.0339 | 0.5 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | AUR protein kinase | 0.0127 | 0.0339 | 0.0587 |
Loa Loa (eye worm) | AUR protein kinase | 0.0127 | 0.0339 | 0.0587 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0792 | 0.5771 | 1 |
Onchocerca volvulus | 0.0153 | 0.0552 | 0.5 | |
Giardia lamblia | Aurora kinase | 0.0127 | 0.0339 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0127 | 0.0339 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.131 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0127 | 0.0339 | 0.0587 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0348 | 0.214 | 1 |
Echinococcus granulosus | aurora kinase A | 0.0127 | 0.0339 | 0.0339 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0127 | 0.0339 | 0.0427 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.131 | 1 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0153 | 0.0552 | 0.0957 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQI | 0.0192 | 0.0868 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0792 | 0.5771 | 1 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0127 | 0.0339 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0127 | 0.0339 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0348 | 0.214 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0097 | 0.0167 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0127 | 0.0339 | 0.0339 |
Leishmania major | protein kinase, putative | 0.0127 | 0.0339 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0192 | 0.0868 | 0.2937 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0127 | 0.0339 | 0.0587 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqI | 0.0192 | 0.0868 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0153 | 0.0552 | 0.0552 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0127 | 0.0339 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0127 | 0.0339 | 0.0427 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0097 | 0.0097 | 0.0097 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0127 | 0.0339 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.