Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0063 | 0.9981 | 0.997 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0019 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3796 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 1 | 1 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Chlamydia trachomatis | glutamine binding protein | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.3796 | 0.2525 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 1 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.3796 | 0.2525 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3796 | 0.5 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0063 | 0.9981 | 0.9978 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0063 | 0.9981 | 0.9978 |
Brugia malayi | TAR-binding protein | 0.0063 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3796 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 1 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 1 | 0.5 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0019 | 0 | 0.5 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0019 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.3796 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.