Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0028 | 0.4732 | 0.4732 |
Echinococcus multilocularis | lamin | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.4732 | 0.4732 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.726 | 0.726 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0816 | 0.0816 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.726 | 0.726 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Schistosoma mansoni | lamin | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0816 | 0.0816 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Echinococcus multilocularis | musashi | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4732 | 0.4732 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.726 | 0.726 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.4732 | 0.4732 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0037 | 0.726 | 0.726 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.4593 | 0.4593 |
Onchocerca volvulus | 0.0028 | 0.4732 | 1 | |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0816 | 0.0816 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.4732 | 0.4732 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Echinococcus granulosus | lamin | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.726 | 0.726 |
Onchocerca volvulus | 0.0028 | 0.4732 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.