Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | sodium channel, voltage-gated, type IX, alpha subunit | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0172 | 1 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0169 | 0.9747 | 1 |
Echinococcus granulosus | jun protein | 0.0172 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.9747 | 0.9743 |
Brugia malayi | hypothetical protein | 0.0135 | 0.7299 | 0.7299 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.2015 | 0.3387 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0157 | 0.0161 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.9747 | 0.9743 |
Onchocerca volvulus | 0.0135 | 0.7299 | 1 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.1193 | 0.1193 |
Schistosoma mansoni | jun-related protein | 0.014 | 0.7644 | 0.9519 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.1193 | 0.1193 |
Loa Loa (eye worm) | phosphofructokinase | 0.0113 | 0.5645 | 0.5791 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.803 | 1 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0113 | 0.5645 | 0.5 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0113 | 0.5645 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.2015 | 0.251 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0113 | 0.5645 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0169 | 0.9747 | 0.9743 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.2015 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0113 | 0.5645 | 0.5645 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0045 | 0.0733 | 0.105 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0113 | 0.5645 | 0.7029 |
Echinococcus multilocularis | jun protein | 0.0172 | 1 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0113 | 0.5645 | 0.5791 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.2015 | 0.251 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.2015 | 0.1888 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0113 | 0.5645 | 0.7029 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0172 | 1 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0113 | 0.5645 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1193 | 0.1224 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0113 | 0.5645 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0113 | 0.5645 | 0.5575 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0113 | 0.5645 | 0.5575 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0157 | 0.0195 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.2015 | 0.1888 |
Brugia malayi | phosphofructokinase | 0.0113 | 0.5645 | 0.5645 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.9655 | 0.9906 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0113 | 0.5645 | 0.5791 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.7644 | 0.9519 |
Echinococcus multilocularis | sodium channel protein | 0.0045 | 0.0733 | 0.0585 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0113 | 0.5645 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Echinococcus granulosus | sodium channel protein | 0.0045 | 0.0733 | 0.0585 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0169 | 0.9747 | 0.9747 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 0.5645 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0113 | 0.5645 | 0.5645 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.1193 | 0.1224 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0045 | 0.0733 | 0.0585 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0113 | 0.5645 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.803 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.