Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0384 | 0.3471 | 0.0537 |
Echinococcus granulosus | dual specificity | 0.0384 | 0.3471 | 0.2583 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK2 protein kinase | 0.0384 | 0.3471 | 0.2583 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0354 | 0.31 | 0.2494 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0354 | 0.31 | 0.2162 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0821 | 0.8829 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0384 | 0.3471 | 0.0537 |
Loa Loa (eye worm) | hypothetical protein | 0.0801 | 0.8589 | 0.8397 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0354 | 0.31 | 0.2162 |
Loa Loa (eye worm) | hypothetical protein | 0.0801 | 0.8589 | 0.8397 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0354 | 0.31 | 0.2162 |
Echinococcus multilocularis | dual specificity | 0.0384 | 0.3471 | 0.2583 |
Echinococcus granulosus | dual specificity | 0.0821 | 0.8829 | 0.8669 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0384 | 0.3471 | 0.0537 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0384 | 0.3471 | 0.0537 |
Echinococcus multilocularis | dual specificity | 0.0821 | 0.8829 | 0.8669 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0354 | 0.31 | 0.2162 |
Brugia malayi | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | 0.0384 | 0.3471 | 0.2583 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0821 | 0.8829 | 0.8302 |
Toxoplasma gondii | cell-cycle-associated protein kinase DYRK2, putative | 0.0384 | 0.3471 | 0.0537 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0354 | 0.31 | 0.31 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.286 | 0.1889 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0354 | 0.31 | 0.2162 |
Echinococcus multilocularis | 0.0896 | 0.976 | 0.9727 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0354 | 0.31 | 0.2162 |
Entamoeba histolytica | hypothetical protein | 0.0821 | 0.8829 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0231 | 0.1585 | 0.044 |
Entamoeba histolytica | protein kinase, putative | 0.0821 | 0.8829 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0821 | 0.8829 | 0.8669 |
Entamoeba histolytica | protein kinase, putative | 0.0821 | 0.8829 | 1 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0821 | 0.8829 | 0.8829 |
Brugia malayi | cell division control protein 2 homolog | 0.0354 | 0.31 | 0.2162 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0821 | 0.8829 | 0.8302 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0821 | 0.8829 | 0.8302 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0231 | 0.1585 | 0.044 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0384 | 0.3471 | 0.0537 |
Echinococcus granulosus | dual specificity | 0.0384 | 0.3471 | 0.2583 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0354 | 0.31 | 0.2162 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0354 | 0.31 | 0.2162 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0821 | 0.8829 | 0.8669 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0384 | 0.3471 | 0.2583 |
Brugia malayi | Protein kinase domain containing protein | 0.0821 | 0.8829 | 0.8669 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0354 | 0.31 | 0.2162 |
Entamoeba histolytica | protein kinase, putative | 0.0384 | 0.3471 | 0.298 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0386 | 0.3488 | 0.3001 |
Trypanosoma brucei | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0384 | 0.3471 | 0.3471 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0354 | 0.31 | 0.31 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0354 | 0.31 | 0.2162 |
Brugia malayi | Protein kinase domain containing protein | 0.0354 | 0.31 | 0.2162 |
Trypanosoma cruzi | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0384 | 0.3471 | 0.0537 |
Loa Loa (eye worm) | hypothetical protein | 0.0896 | 0.976 | 0.9727 |
Echinococcus multilocularis | dual specificity | 0.0384 | 0.3471 | 0.2583 |
Giardia lamblia | Kinase, CMGC DYRK | 0.0384 | 0.3471 | 0.0537 |
Leishmania major | protein kinase, putative,dual-specificity protein kinase, putative | 0.0384 | 0.3471 | 0.0537 |
Echinococcus granulosus | cyclin dependent kinase | 0.0354 | 0.31 | 0.2162 |
Echinococcus granulosus | hypothetical protein | 0.0896 | 0.976 | 0.9727 |
Echinococcus granulosus | dual specificity | 0.0384 | 0.3471 | 0.2583 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0384 | 0.3471 | 0.298 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0354 | 0.31 | 0.2162 |
Echinococcus multilocularis | dual specificity | 0.0384 | 0.3471 | 0.2583 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0384 | 0.3471 | 0.0537 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0354 | 0.31 | 0.2162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.