Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Animal haem peroxidase family protein | 0.0032 | 0.0062 | 0.0062 |
Onchocerca volvulus | Peroxidase homolog | 0.0032 | 0.0062 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0032 | 0.0062 | 0.0062 |
Onchocerca volvulus | Peroxidasin homolog | 0.0032 | 0.0062 | 0.5 |
Onchocerca volvulus | 0.0032 | 0.0062 | 0.5 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Schistosoma mansoni | fatty acid binding protein | 0.0183 | 0.2566 | 1 |
Onchocerca volvulus | 0.0032 | 0.0062 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Onchocerca volvulus | Dual oxidase homolog | 0.0032 | 0.0062 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Schistosoma mansoni | fatty acid binding protein | 0.0183 | 0.2566 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0032 | 0.0062 | 0.5 |
Brugia malayi | Blistered cuticle protein 3 | 0.0032 | 0.0062 | 0.0062 |
Brugia malayi | Animal haem peroxidase family protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | lipocalin/cytosolic fatty-acid binding protein family protein | 0.0631 | 1 | 1 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0183 | 0.2566 | 1 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0183 | 0.2566 | 1 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0072 | 0.073 | 0.2666 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0183 | 0.2566 | 1 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0072 | 0.073 | 0.2666 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0032 | 0.0062 | 0.0062 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0032 | 0.0062 | 0.5 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0183 | 0.2566 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0032 | 0.0062 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0032 | 0.0062 | 0.0062 |
Brugia malayi | Animal haem peroxidase family protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Brugia malayi | Animal haem peroxidase family protein | 0.0032 | 0.0062 | 0.0062 |
Brugia malayi | Peroxidasin | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0032 | 0.0062 | 0.0062 |
Onchocerca volvulus | 0.0032 | 0.0062 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Echinococcus granulosus | fatty acid binding protein, adipocyte | 0.0072 | 0.073 | 0.2666 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0062 | 0.0062 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.