Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | glutamate receptor, metabotropic 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | SET domain-containing protein | 0.1494 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor | 0.0061 | 0.0252 | 0.0252 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0051 | 0.0185 | 0.0146 |
Echinococcus multilocularis | histone lysine N methyltransferase E(z) | 0.1494 | 1 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0061 | 0.0252 | 0.0214 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0055 | 0.0213 | 0.0175 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0075 | 0.0348 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0348 | 0.0348 |
Echinococcus granulosus | histone lysine N methyltransferase Ez | 0.1494 | 1 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0075 | 0.0348 | 0.0167 |
Schistosoma mansoni | enhancer of zeste ezh | 0.1494 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0069 | 0.0309 | 0.0271 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.