Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | roundabout 2 | 0.0216 | 0.0148 | 0.0209 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0483 | 0.066 | 1 |
Echinococcus multilocularis | MAM | 0.0632 | 0.0946 | 0.1912 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0729 | 0.1132 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0182 | 0.0034 |
Schistosoma mansoni | hypothetical protein | 0.0632 | 0.0946 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0246 | 0.0205 | 0.3111 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0148 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0632 | 0.0946 | 0.0901 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0246 | 0.0205 | 0.3111 |
Loa Loa (eye worm) | hypothetical protein | 0.2538 | 0.4607 | 0.4581 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0148 | 0.0098 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0216 | 0.0148 | 0.2238 |
Echinococcus granulosus | MAM | 0.0632 | 0.0946 | 0.1912 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0729 | 0.1132 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.4644 | 0.8651 | 0.8647 |
Loa Loa (eye worm) | TK protein kinase | 0.2607 | 0.4739 | 0.4714 |
Echinococcus multilocularis | tyrosine protein kinase | 0.2607 | 0.4739 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0632 | 0.0946 | 0.0901 |
Echinococcus multilocularis | roundabout 2 | 0.0216 | 0.0148 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0632 | 0.0946 | 0.0901 |
Schistosoma mansoni | hypothetical protein | 0.0632 | 0.0946 | 1 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0729 | 0.1132 | 0.5 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0344 | 0.0393 | 1 |
Onchocerca volvulus | 0.0683 | 0.1044 | 1 | |
Brugia malayi | hypothetical protein | 0.0632 | 0.0946 | 0.0811 |
Brugia malayi | Protein kinase domain containing protein | 0.2607 | 0.4739 | 0.466 |
Schistosoma mansoni | nephrin | 0.0216 | 0.0148 | 0.1093 |
Echinococcus granulosus | tyrosine protein kinase | 0.2607 | 0.4739 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0148 | 0.0098 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0246 | 0.0205 | 0.5229 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0234 | 0.0182 | 0.0133 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0344 | 0.0393 | 0.5951 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0344 | 0.0393 | 0.5951 |
Schistosoma mansoni | cell adhesion molecule | 0.0216 | 0.0148 | 0.1093 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.5345 | 0.9997 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.