Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0126 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.2702 | 0.9749 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2642 | 0.9524 | 0.977 |
Schistosoma mansoni | thyroid hormone receptor | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0126 | 0 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.2702 | 0.9749 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0126 | 0 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0126 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.