Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nephrin | 0.0216 | 0.0148 | 0.1093 |
Brugia malayi | Protein kinase domain containing protein | 0.2607 | 0.4739 | 0.466 |
Brugia malayi | hypothetical protein | 0.0632 | 0.0946 | 0.0811 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0344 | 0.0393 | 1 |
Onchocerca volvulus | 0.0683 | 0.1044 | 1 | |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.5345 | 0.9997 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0216 | 0.0148 | 0.1093 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0344 | 0.0393 | 0.5951 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0234 | 0.0182 | 0.0133 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0344 | 0.0393 | 0.5951 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0246 | 0.0205 | 0.5229 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0148 | 0.0098 |
Echinococcus granulosus | tyrosine protein kinase | 0.2607 | 0.4739 | 1 |
Echinococcus multilocularis | tyrosine protein kinase | 0.2607 | 0.4739 | 1 |
Loa Loa (eye worm) | TK protein kinase | 0.2607 | 0.4739 | 0.4714 |
Loa Loa (eye worm) | hypothetical protein | 0.4644 | 0.8651 | 0.8647 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0729 | 0.1132 | 0.5 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0729 | 0.1132 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0632 | 0.0946 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0632 | 0.0946 | 0.0901 |
Echinococcus multilocularis | roundabout 2 | 0.0216 | 0.0148 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0632 | 0.0946 | 0.0901 |
Loa Loa (eye worm) | hypothetical protein | 0.2538 | 0.4607 | 0.4581 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0246 | 0.0205 | 0.3111 |
Loa Loa (eye worm) | hypothetical protein | 0.0632 | 0.0946 | 0.0901 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0148 | 0.0098 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0246 | 0.0205 | 0.3111 |
Schistosoma mansoni | hypothetical protein | 0.0632 | 0.0946 | 1 |
Echinococcus granulosus | MAM | 0.0632 | 0.0946 | 0.1912 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0216 | 0.0148 | 0.2238 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0148 | 0.0098 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0483 | 0.066 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0216 | 0.0148 | 0.0209 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0729 | 0.1132 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0234 | 0.0182 | 0.0034 |
Echinococcus multilocularis | MAM | 0.0632 | 0.0946 | 0.1912 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.