Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0178 | 0.0844 | 0.0844 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1568 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.1568 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1568 | 1 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1568 | 1 | 0.5 |
Onchocerca volvulus | 0.0103 | 0.0349 | 0.5 | |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1568 | 1 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0178 | 0.0844 | 0.0844 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1568 | 1 | 0.5 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0251 | 0.1327 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1568 | 1 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.068 | 0.068 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1568 | 1 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1568 | 1 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1568 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1568 | 1 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1568 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0178 | 0.0844 | 0.0844 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1568 | 1 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.068 | 0.068 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1568 | 1 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0178 | 0.0844 | 0.0844 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1568 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1568 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1568 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1568 | 1 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1568 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1568 | 1 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0178 | 0.0844 | 0.0844 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.