Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 0.0104 | 1 |
Echinococcus multilocularis | liprin beta 1 | 0.0117 | 0.0104 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0104 | 0.0104 |
Onchocerca volvulus | 0.0117 | 0.0104 | 0.5 | |
Echinococcus multilocularis | tankyrase | 0.0117 | 0.0104 | 0.0096 |
Plasmodium falciparum | tyrosine kinase-like protein | 0.0117 | 0.0104 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0104 | 0.0104 |
Brugia malayi | sterile alpha and TIR motif containing protein 1 isoform a | 0.0117 | 0.0104 | 0.0096 |
Echinococcus granulosus | liprin beta 1 | 0.0117 | 0.0104 | 0.0096 |
Plasmodium vivax | tyrosine kinase-like protein, putative | 0.0117 | 0.0104 | 0.5 |
Echinococcus multilocularis | sterile alpha and tir motif containing protein | 0.0117 | 0.0104 | 0.0096 |
Echinococcus granulosus | SAM domain containing protein | 0.0117 | 0.0104 | 0.0096 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 0.0104 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0801 | 0.1007 | 0.0995 |
Schistosoma mansoni | Protein orai-1 | 0.761 | 1 | 1 |
Schistosoma mansoni | lip-related protein (liprin) alpha | 0.0117 | 0.0104 | 0.0091 |
Trichomonas vaginalis | c2h2 zinc finger protein, putative | 0.0117 | 0.0104 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0044 | 0.0008 | 0.0008 |
Echinococcus multilocularis | stromal interaction molecule 1 | 0.1477 | 0.19 | 0.1894 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.0104 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.1477 | 0.19 | 0.19 |
Brugia malayi | Neurabin protein 1 | 0.0117 | 0.0104 | 0.0096 |
Brugia malayi | Tnks protein | 0.0117 | 0.0104 | 0.0096 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.0104 | 0.0091 |
Echinococcus multilocularis | liprin alpha 2 | 0.0117 | 0.0104 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0104 | 0.0104 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 0.0104 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.761 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0117 | 0.0104 | 0.0096 |
Echinococcus granulosus | tankyrase | 0.0117 | 0.0104 | 0.0096 |
Echinococcus multilocularis | calcium release activated calcium channel | 0.761 | 1 | 1 |
Schistosoma mansoni | tankyrase | 0.0117 | 0.0104 | 0.0091 |
Onchocerca volvulus | 0.0117 | 0.0104 | 0.5 | |
Echinococcus granulosus | liprin alpha 2 | 0.0117 | 0.0104 | 0.0096 |
Schistosoma mansoni | lar interacting protein (lip)-related protein | 0.0117 | 0.0104 | 0.0091 |
Brugia malayi | hypothetical protein | 0.1477 | 0.19 | 0.1894 |
Toxoplasma gondii | Tyrosine kinase-like (TKL) protein | 0.0117 | 0.0104 | 0.5 |
Schistosoma mansoni | Protein orai-1 | 0.761 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 0.0104 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0858 | 0.1083 | 0.1076 |
Loa Loa (eye worm) | toll and interleukin 1 receptor domain-containing protein isoform f | 0.0117 | 0.0104 | 0.0104 |
Echinococcus granulosus | calcium release activated calcium channel | 0.761 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.0104 | 0.0091 |
Echinococcus granulosus | sterile alpha and tir motif containing protein | 0.0117 | 0.0104 | 0.0096 |
Brugia malayi | Serotonin receptor | 0.4857 | 0.6364 | 0.6361 |
Echinococcus multilocularis | SAM domain containing protein | 0.0117 | 0.0104 | 0.0096 |
Echinococcus granulosus | Sterile alpha motif SAM | 0.0117 | 0.0104 | 0.0096 |
Echinococcus granulosus | stromal interaction molecule 1 | 0.1477 | 0.19 | 0.1894 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0104 | 0.0104 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0827 | 0.1042 | 0.1035 |
Schistosoma mansoni | hypothetical protein | 0.0676 | 0.0842 | 0.083 |
Plasmodium falciparum | protein kinase, putative | 0.0117 | 0.0104 | 0.5 |
Brugia malayi | coiled-coil like protein 1 | 0.0117 | 0.0104 | 0.0096 |
Schistosoma mansoni | sarm1 | 0.0117 | 0.0104 | 0.0091 |
Brugia malayi | Liprin-alpha 2 | 0.0117 | 0.0104 | 0.0096 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.