Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hypothetical protein | 0.0946 | 0.3168 | 0.0322 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.1614 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0668 | 0.0329 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0946 | 0.3168 | 0.3168 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.1614 | 1 | 1 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.1614 | 1 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.1614 | 1 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.1614 | 1 | 1 |
Echinococcus granulosus | Ion_trans_N domain containing protein | 0.0946 | 0.3168 | 0.0322 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.1614 | 1 | 1 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.1614 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0924 | 0.2941 | 0.2941 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Stimulation of purified Staphylococcus aureus FtsZ polymerization at 40 ug/ml by microtiter plate based light-scattering assay in presence of 10 mM depolymerizing agent GDP | ChEMBL. | 23891185 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.