Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2922 | 0.2922 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0144 | 0.7194 | 0.7194 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0143 | 0.7093 | 0.655 |
Echinococcus multilocularis | endoplasmin | 0.0143 | 0.7093 | 0.7093 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.018 | 1 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.018 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor 4 | 0.009 | 0.2922 | 0.2922 |
Echinococcus granulosus | heat shock protein | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2922 | 0.2922 |
Echinococcus granulosus | glutamate receptor 4 | 0.009 | 0.2922 | 0.2922 |
Schistosoma mansoni | endoplasmin | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0064 | 0.081 | 0.081 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0143 | 0.7093 | 0.655 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.018 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0064 | 0.081 | 0.081 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Plasmodium vivax | heat shock protein 86, putative | 0.018 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.018 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0143 | 0.7093 | 0.655 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0154 | 0.8004 | 0.8004 |
Schistosoma mansoni | heat shock protein | 0.018 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0143 | 0.7093 | 0.7093 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Trichomonas vaginalis | endoplasmin, putative | 0.011 | 0.4483 | 0.345 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0154 | 0.8004 | 0.8004 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0143 | 0.7093 | 0.5 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.018 | 1 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.018 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0064 | 0.081 | 0.081 |
Schistosoma mansoni | heat shock protein | 0.018 | 1 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.018 | 1 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.018 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0064 | 0.081 | 0.081 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0074 | 0.1576 | 0.5 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Plasmodium vivax | endoplasmin, putative | 0.018 | 1 | 1 |
Schistosoma mansoni | heat shock protein | 0.0074 | 0.1576 | 0.1576 |
Loa Loa (eye worm) | heat shock protein 90 | 0.018 | 1 | 1 |
Plasmodium falciparum | endoplasmin, putative | 0.011 | 0.4483 | 0.345 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0143 | 0.7093 | 0.7093 |
Echinococcus granulosus | glutamate receptor 1 | 0.009 | 0.2922 | 0.2922 |
Trichomonas vaginalis | heat shock protein, putative | 0.018 | 1 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0135 | 0.6423 | 0.6423 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.018 | 1 | 1 |
Echinococcus multilocularis | heat shock protein | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0144 | 0.7194 | 0.7194 |
Entamoeba histolytica | heat shock protein 90, putative | 0.018 | 1 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.018 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0135 | 0.6423 | 0.6423 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0106 | 0.4152 | 0.3058 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0143 | 0.7093 | 0.5 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0143 | 0.7093 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.018 | 1 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.018 | 1 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.018 | 1 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0143 | 0.7093 | 0.5 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.018 | 1 | 1 |
Brugia malayi | heat shock protein 90 | 0.018 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0143 | 0.7093 | 0.5 |
Echinococcus granulosus | glutamate receptor 2 | 0.0154 | 0.8004 | 0.8004 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0074 | 0.1576 | 0.1576 |
Treponema pallidum | heat shock protein 90 | 0.0143 | 0.7093 | 0.5 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0144 | 0.7194 | 0.6669 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.011 | 0.4503 | 0.4503 |
Schistosoma mansoni | endoplasmin | 0.018 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2922 | 0.2922 |
Toxoplasma gondii | heat shock protein HSP90 | 0.018 | 1 | 1 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0074 | 0.1576 | 0.1576 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0064 | 0.081 | 0.081 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.011 | 0.4503 | 0.4503 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0144 | 0.7194 | 0.6669 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0143 | 0.7093 | 0.655 |
Trichomonas vaginalis | heat shock protein, putative | 0.0143 | 0.7093 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0064 | 0.081 | 0.081 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0074 | 0.1576 | 0.1576 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.018 | 1 | 1 |
Echinococcus granulosus | endoplasmin | 0.0143 | 0.7093 | 0.7093 |
Leishmania major | heat shock protein 83-1 | 0.018 | 1 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0143 | 0.7093 | 0.7093 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0154 | 0.8004 | 0.8004 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0064 | 0.081 | 0.081 |
Trichomonas vaginalis | heat shock protein, putative | 0.011 | 0.4483 | 0.345 |
Trypanosoma brucei | heat shock protein 90, putative | 0.018 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.