Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Cyclin A | 0.0713 | 0.2178 | 0.1069 |
Giardia lamblia | Hypothetical protein | 0.0713 | 0.2178 | 0.1069 |
Echinococcus granulosus | 6 phosphofructo 2 kinase:fructose 2 | 0.099 | 0.4197 | 0.4197 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.0973 | 0.4075 | 0.4038 |
Schistosoma mansoni | cyclin B3 | 0.0713 | 0.2178 | 0.2178 |
Schistosoma mansoni | cyclin d | 0.0511 | 0.0709 | 0.0709 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1786 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1786 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.1786 | 1 | 1 |
Echinococcus granulosus | cyclin B | 0.0713 | 0.2178 | 0.2178 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.099 | 0.4197 | 0.4197 |
Brugia malayi | Protein kinase domain containing protein | 0.1786 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.1786 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0713 | 0.2178 | 0.1581 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1786 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.099 | 0.4197 | 0.4161 |
Echinococcus granulosus | cyclin dependent kinase | 0.1786 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0973 | 0.4075 | 0.4038 |
Trypanosoma cruzi | cyclin, putative | 0.0713 | 0.2178 | 0.2129 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0713 | 0.2178 | 0.2129 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.1786 | 1 | 1 |
Echinococcus granulosus | cyclins | 0.0713 | 0.2178 | 0.2178 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1786 | 1 | 1 |
Plasmodium falciparum | protein kinase 5 | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Schistosoma mansoni | cyclin B | 0.0713 | 0.2178 | 0.2178 |
Entamoeba histolytica | cyclin family protein | 0.0713 | 0.2178 | 0.1069 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclin B3 1 | 0.0713 | 0.2178 | 0.2178 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0511 | 0.0709 | 0.0709 |
Echinococcus granulosus | cyclins | 0.0713 | 0.2178 | 0.2178 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0713 | 0.2178 | 0.2178 |
Loa Loa (eye worm) | hypothetical protein | 0.0973 | 0.4075 | 0.3623 |
Echinococcus granulosus | cyclin b3 | 0.0713 | 0.2178 | 0.2178 |
Plasmodium vivax | protein kinase Crk2 | 0.1786 | 1 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0584 | 0.1241 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.1786 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.099 | 0.4197 | 0.3754 |
Giardia lamblia | Kinase, CMGC CDK | 0.1786 | 1 | 1 |
Echinococcus granulosus | cyclins | 0.0713 | 0.2178 | 0.2178 |
Leishmania major | cyclin | 0.0713 | 0.2178 | 0.2129 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.1786 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0973 | 0.4075 | 0.4038 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0973 | 0.4075 | 0.4038 |
Entamoeba histolytica | cyclin, putative | 0.0713 | 0.2178 | 0.1069 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.1786 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.1786 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.1786 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.0584 | 0.1241 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0713 | 0.2178 | 0.1581 |
Entamoeba histolytica | cyclin family protein | 0.0713 | 0.2178 | 0.1069 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.099 | 0.4197 | 0.4161 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclin b3 | 0.0713 | 0.2178 | 0.2178 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.1786 | 1 | 1 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0511 | 0.0709 | 0.0709 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0713 | 0.2178 | 0.1581 |
Echinococcus multilocularis | cyclin dependent kinase | 0.1786 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0567 | 0.1119 | 0.0442 |
Echinococcus multilocularis | cyclin B | 0.0713 | 0.2178 | 0.2178 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.1786 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0713 | 0.2178 | 0.1581 |
Loa Loa (eye worm) | hypothetical protein | 0.1747 | 0.9717 | 0.9696 |
Echinococcus granulosus | cyclins | 0.0713 | 0.2178 | 0.2178 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.1786 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.1786 | 1 | 1 |
Schistosoma mansoni | cyclins | 0.0713 | 0.2178 | 0.2178 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Echinococcus granulosus | cyclins | 0.0713 | 0.2178 | 0.2178 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0713 | 0.2178 | 0.1581 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0713 | 0.2178 | 0.1069 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0713 | 0.2178 | 0.2129 |
Echinococcus granulosus | cyclin B3 1 | 0.0713 | 0.2178 | 0.2178 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0713 | 0.2178 | 0.2129 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.1786 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.1786 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0713 | 0.2178 | 0.1581 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0713 | 0.2178 | 0.2178 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.099 | 0.4197 | 0.4161 |
Trypanosoma cruzi | cyclin 6, putative | 0.0713 | 0.2178 | 0.2129 |
Trypanosoma cruzi | cyclin, putative | 0.0713 | 0.2178 | 0.2129 |
Echinococcus multilocularis | cyclins | 0.0713 | 0.2178 | 0.2178 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.099 | 0.4197 | 0.4161 |
Onchocerca volvulus | 0.099 | 0.4197 | 1 | |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.1786 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.1786 | 1 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.099 | 0.4197 | 0.4197 |
Entamoeba histolytica | cyclin, putative | 0.0713 | 0.2178 | 0.1069 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.