Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | farnesyltransferase beta subunit | 0.0384 | 0.0201 | 0.5 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.055 | 0.0523 | 1 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.055 | 0.0523 | 1 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.055 | 0.0523 | 0.0328 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0384 | 0.0201 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2204 | 0.3717 | 0.3588 |
Loa Loa (eye worm) | hypothetical protein | 0.2204 | 0.3717 | 0.3588 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.055 | 0.0523 | 1 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.0384 | 0.0201 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.2204 | 0.3717 | 0.3588 |
Loa Loa (eye worm) | STE/STE7/MEK7 protein kinase | 0.5457 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.2204 | 0.3717 | 0.3588 |
Echinococcus multilocularis | dual specificity mitogen activated protein | 0.5457 | 1 | 1 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.055 | 0.0523 | 1 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.055 | 0.0523 | 0.0328 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0384 | 0.0201 | 0.5 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.055 | 0.0523 | 0.0328 |
Echinococcus granulosus | dual specificity mitogen activated protein | 0.5457 | 1 | 1 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.055 | 0.0523 | 1 |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.0384 | 0.0201 | 0.3849 |
Schistosoma mansoni | protein kinase | 0.5457 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.055 | 0.0523 | 0.0328 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.055 | 0.0523 | 1 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.055 | 0.0523 | 0.0328 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.055 | 0.0523 | 0.0328 |
Echinococcus multilocularis | serotonin receptor | 0.2204 | 0.3717 | 0.3588 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0408 | 0.0247 | 0.1427 |
Toxoplasma gondii | hypothetical protein | 0.0408 | 0.0247 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.2204 | 0.3717 | 0.3588 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.055 | 0.0523 | 1 |
Loa Loa (eye worm) | STE/STE7/MEK7 protein kinase | 0.5457 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.