Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Fibulin-1 precursor | 0.0061 | 0.0233 | 0.0237 |
Echinococcus granulosus | Tolloid protein 1 | 0.0191 | 0.1216 | 0.1237 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0356 | 0.0362 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0191 | 0.1216 | 0.1216 |
Schistosoma mansoni | egf-like domain protein | 0.0055 | 0.0186 | 0.0186 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0061 | 0.0233 | 0.5 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0061 | 0.0233 | 0.0237 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0047 | 0.0123 | 0.0125 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.1322 | 0.9837 | 1 |
Echinococcus multilocularis | laminin | 0.0061 | 0.0233 | 0.0237 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0191 | 0.1216 | 0.1237 |
Loa Loa (eye worm) | hypothetical protein | 0.1322 | 0.9837 | 1 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.1322 | 0.9837 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0123 | 0.0125 |
Brugia malayi | Protein kinase domain containing protein | 0.1322 | 0.9837 | 1 |
Loa Loa (eye worm) | AStacin protease | 0.0119 | 0.0672 | 0.0684 |
Onchocerca volvulus | Putative cubilin | 0.0047 | 0.0123 | 0.6617 |
Onchocerca volvulus | Arrow homolog | 0.0055 | 0.0186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1322 | 0.9837 | 1 |
Echinococcus granulosus | laminin | 0.0061 | 0.0233 | 0.0237 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0055 | 0.0186 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0233 | 0.0237 |
Loa Loa (eye worm) | TKL/MLK/LZK protein kinase | 0.1322 | 0.9837 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0061 | 0.0233 | 0.5 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0191 | 0.1216 | 0.1237 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0186 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0186 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.1157 | 0.1177 |
Echinococcus multilocularis | fibrillin 1 | 0.0061 | 0.0233 | 0.0237 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0055 | 0.0186 | 0.0189 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0061 | 0.0233 | 0.0237 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.