Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | protein kinase | 0.2794 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0079 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | STE/STE7/MEK7 protein kinase | 0.2794 | 1 | 1 |
Echinococcus granulosus | dual specificity mitogen activated protein | 0.2794 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0118 | 0.0113 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0146 | 0.0368 | 0.0368 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0079 | 0.0121 | 0.0116 |
Schistosoma mansoni | tyrosine kinase | 0.0079 | 0.0121 | 0.0116 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0047 | 0.0005 | 0.0005 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0146 | 0.0368 | 0.0362 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0079 | 0.0121 | 0.0116 |
Schistosoma mansoni | tyrosine kinase | 0.0146 | 0.0368 | 0.0362 |
Schistosoma mansoni | tyrosine kinase | 0.0079 | 0.0121 | 0.0116 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0118 | 0.0113 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0118 | 0.0113 |
Echinococcus multilocularis | dual specificity mitogen activated protein | 0.2794 | 1 | 1 |
Echinococcus multilocularis | insulin receptor | 0.0047 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0146 | 0.0368 | 0.0362 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0146 | 0.0368 | 0.0362 |
Loa Loa (eye worm) | STE/STE7/MEK7 protein kinase | 0.2794 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.