Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | geminin | 0.0195 | 0.4918 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0397 | 0.0728 |
Schistosoma mansoni | lamin | 0.0031 | 0.0397 | 0.0728 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.0993 | 0.195 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0397 | 0.0397 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.0993 | 0.195 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.0993 | 0.0993 |
Echinococcus granulosus | lamin | 0.0031 | 0.0397 | 0.0728 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0397 | 0.0728 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0042 | 0.0042 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.0993 | 0.195 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0397 | 0.0397 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.1123 | 0.1123 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0397 | 0.0728 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.0993 | 0.0993 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0397 | 0.0728 |
Echinococcus multilocularis | geminin | 0.0195 | 0.4918 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0382 | 0.0382 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.0993 | 0.195 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.1123 | 0.1123 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0623 | 0.0623 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0397 | 0.0397 |
Onchocerca volvulus | 0.038 | 1 | 1 | |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0397 | 0.0397 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0397 | 0.0728 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0623 | 0.0623 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0623 | 0.1191 |
Schistosoma mansoni | lamin | 0.0031 | 0.0397 | 0.0728 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0397 | 0.0397 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.038 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.4918 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.4918 | 1 |
Onchocerca volvulus | 0.038 | 1 | 1 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.1123 | 0.1123 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.0993 | 0.195 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1123 | 0.1123 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.0993 | 0.195 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0397 | 0.0728 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0042 | 0.0042 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.0993 | 0.195 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.