Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter 1E | 0.0031 | 0.1479 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 1 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0101 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Leishmania major | glucose transporter, lmgt3 | 0.0031 | 0.1479 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Trypanosoma cruzi | hexose transporter | 0.0031 | 0.1479 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0101 | 1 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus multilocularis | General substrate transporter | 0.0087 | 0.8263 | 0.8263 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Leishmania major | glucose transporter, lmgt2 | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Echinococcus granulosus | General substrate transporter | 0.0087 | 0.8263 | 0.8263 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0019 | 0 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma cruzi | hexose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Plasmodium falciparum | hexose transporter | 0.0101 | 1 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0101 | 1 | 1 |
Trypanosoma brucei | glucose transporter 2A | 0.0031 | 0.1479 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0031 | 0.1479 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma cruzi | hexose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Leishmania major | glucose transporter, lmgt1 | 0.0031 | 0.1479 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0101 | 1 | 1 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0101 | 1 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0101 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0101 | 1 | 1 |
Loa Loa (eye worm) | sugar transporter | 0.0101 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0031 | 0.1479 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.