Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.3758 | 0.9815 | 0.9706 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3822 | 1 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3758 | 0.9815 | 0.9706 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0341 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.2256 | 0.55 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.2256 | 0.55 | 1 |
Giardia lamblia | Hypothetical protein | 0.2256 | 0.55 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3758 | 0.9815 | 0.9604 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.2256 | 0.55 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.2256 | 0.55 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.3822 | 1 | 0.5 |
Onchocerca volvulus | 0.3822 | 1 | 0.5 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3758 | 0.9815 | 0.9706 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3758 | 0.9815 | 0.9706 |
Loa Loa (eye worm) | hypothetical protein | 0.3822 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.