Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3822 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.2256 | 0.55 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3758 | 0.9815 | 0.9706 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Onchocerca volvulus | 0.3822 | 1 | 0.5 | |
Schistosoma mansoni | 6-phosphofructokinase | 0.3822 | 1 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.3758 | 0.9815 | 0.9706 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0341 | 0 | 0.5 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.2256 | 0.55 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3758 | 0.9815 | 0.9706 |
Giardia lamblia | Hypothetical protein | 0.2256 | 0.55 | 1 |
Giardia lamblia | Hypothetical protein | 0.2256 | 0.55 | 1 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3822 | 1 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3758 | 0.9815 | 0.9706 |
Loa Loa (eye worm) | hypothetical protein | 0.3758 | 0.9815 | 0.9604 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0341 | 0 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3822 | 1 | 1 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.2256 | 0.55 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.