Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0094 | 0 | 0.5 |
Onchocerca volvulus | 0.0094 | 0 | 0.5 | |
Giardia lamblia | Kinase, CMGC GSK | 0.0094 | 0 | 0.5 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0094 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0426 | 0.5715 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0094 | 0 | 0.5 |
Brugia malayi | Hint module family protein | 0.0159 | 0.1119 | 1 |
Echinococcus granulosus | Desert hedgehog protein | 0.0585 | 0.8448 | 0.8448 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0094 | 0 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0094 | 0 | 0.5 |
Echinococcus multilocularis | smoothened | 0.0675 | 1 | 1 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0094 | 0 | 0.5 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0094 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0661 | 0.976 | 1 |
Brugia malayi | Hint module family protein | 0.0159 | 0.1119 | 1 |
Echinococcus multilocularis | hedgehog | 0.0585 | 0.8448 | 0.8448 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1119 | 0.1147 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0094 | 0 | 0.5 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0094 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1119 | 0.1147 |
Entamoeba histolytica | protein kinase, putative | 0.0094 | 0 | 0.5 |
Giardia lamblia | Kinase, CMGC GSK | 0.0094 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0094 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.