Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Aldose reductase | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0019 | 0.186 | 0.162 |
Loa Loa (eye worm) | oxidoreductase | 0.0065 | 1 | 1 |
Onchocerca volvulus | 0.0065 | 1 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.0019 | 0.186 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0065 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0019 | 0.186 | 0.186 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0019 | 0.186 | 0.162 |
Trypanosoma cruzi | aldo-keto reductase | 0.0065 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0065 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0065 | 1 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0019 | 0.186 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0065 | 1 | 1 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0019 | 0.186 | 0.162 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0019 | 0.186 | 0.1843 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0019 | 0.186 | 1 |
Onchocerca volvulus | 0.0065 | 1 | 1 | |
Echinococcus granulosus | aldehyde reductase | 0.0046 | 0.6681 | 0.6583 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0046 | 0.6681 | 0.6583 |
Echinococcus granulosus | hypothetical protein | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0019 | 0.186 | 0.186 |
Schistosoma mansoni | pol-related | 0.0065 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0019 | 0.186 | 0.162 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0065 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0065 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0065 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0046 | 0.6681 | 0.5922 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Toxoplasma gondii | aldo-keto reductase | 0.0019 | 0.186 | 0.162 |
Echinococcus multilocularis | aldo keto reductase | 0.0065 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0065 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0065 | 1 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0019 | 0.186 | 0.1843 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Onchocerca volvulus | 0.0065 | 1 | 1 | |
Onchocerca volvulus | 0.0065 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0065 | 1 | 1 |
Onchocerca volvulus | 0.0065 | 1 | 1 | |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0019 | 0.186 | 0.162 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0019 | 0.186 | 0.162 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0019 | 0.186 | 1 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0019 | 0.186 | 0.162 |
Onchocerca volvulus | 0.0065 | 1 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0065 | 1 | 1 |
Schistosoma mansoni | ABC transporter | 0.0008 | 0.002 | 0.002 |
Echinococcus multilocularis | aldo keto reductase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0065 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0065 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0019 | 0.186 | 0.1843 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0065 | 1 | 1 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.001 | 0.0286 | 0.0286 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0019 | 0.186 | 0.162 |
Loa Loa (eye worm) | oxidoreductase | 0.0065 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0065 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0019 | 0.186 | 0.162 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0019 | 0.186 | 0.162 |
Leishmania major | aldo-keto reductase-like protein | 0.0065 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0065 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0065 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0065 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0065 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0065 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0065 | 1 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0019 | 0.186 | 0.162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.