Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.2015 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0169 | 0.0443 | 0.0443 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0271 | 0.0971 | 1 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0194 | 0.0571 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0271 | 0.0971 | 0.0971 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.1558 | 0.7635 | 0.7635 |
Echinococcus granulosus | prolyl endopeptidase | 0.0271 | 0.0971 | 0.0971 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0271 | 0.0971 | 0.0971 |
Loa Loa (eye worm) | hypothetical protein | 0.0879 | 0.4119 | 0.5127 |
Brugia malayi | hypothetical protein | 0.0879 | 0.4119 | 0.4119 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0271 | 0.0971 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0271 | 0.0971 | 0.0971 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.1558 | 0.7635 | 0.7635 |
Trypanosoma cruzi | oligopeptidase b | 0.0271 | 0.0971 | 0.0971 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.1635 | 0.8033 | 0.8033 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0271 | 0.0971 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0271 | 0.0971 | 0.0971 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0271 | 0.0971 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.2015 | 1 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0271 | 0.0971 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1136 | 0.5448 | 0.6782 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.1635 | 0.8033 | 1 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0271 | 0.0971 | 0.0971 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0271 | 0.0971 | 0.1757 |
Toxoplasma gondii | prolyl endopeptidase | 0.0271 | 0.0971 | 0.1757 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0271 | 0.0971 | 0.0971 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0271 | 0.0971 | 0.0971 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0271 | 0.0971 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0271 | 0.0971 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.1635 | 0.8033 | 0.8033 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.0443 | 0.0443 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0271 | 0.0971 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0271 | 0.0971 | 0.0971 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.1635 | 0.8033 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0194 | 0.0571 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0271 | 0.0971 | 0.0971 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.2015 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0271 | 0.0971 | 1 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0271 | 0.0971 | 0.0971 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.2015 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0271 | 0.0971 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.0971 | 0.1208 |
Schistosoma mansoni | amine GPCR | 0.0346 | 0.1357 | 0.1357 |
Echinococcus multilocularis | geminin | 0.0169 | 0.0443 | 0.0443 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0271 | 0.0971 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.2015 | 1 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0271 | 0.0971 | 0.1208 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.1558 | 0.7635 | 0.7635 |
Plasmodium falciparum | peptidase, putative | 0.0271 | 0.0971 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0271 | 0.0971 | 0.0971 |
Trypanosoma cruzi | oligopeptidase b | 0.0271 | 0.0971 | 0.0971 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0271 | 0.0971 | 0.0971 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0271 | 0.0971 | 0.0971 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0271 | 0.0971 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1635 | 0.8033 | 0.8033 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.2015 | 1 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.2015 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.0971 | 0.1208 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0271 | 0.0971 | 0.0971 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0271 | 0.0971 | 0.1208 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0194 | 0.0571 | 0.1034 |
Trichomonas vaginalis | hypothetical protein | 0.0194 | 0.0571 | 0.5884 |
Mycobacterium tuberculosis | Probable peptidase | 0.0271 | 0.0971 | 1 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0271 | 0.0971 | 0.0971 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.2015 | 1 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0271 | 0.0971 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.115 | 0.5523 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0271 | 0.0971 | 0.1757 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0271 | 0.0971 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.1635 | 0.8033 | 0.8033 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0271 | 0.0971 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.