Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0102 | 0.0244 | 0.0244 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Onchocerca volvulus | 0.0863 | 0.8848 | 0.5 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0102 | 0.0244 | 0.0829 |
Loa Loa (eye worm) | hypothetical protein | 0.0863 | 0.8848 | 0.8848 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0922 | 0.0922 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0102 | 0.0244 | 0.042 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0126 | 0.0126 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0102 | 0.0244 | 0.0829 |
Brugia malayi | Protein kinase domain containing protein | 0.0102 | 0.0244 | 0.1342 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0091 | 0.0126 | 0.0427 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0341 | 0.2947 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0102 | 0.0244 | 0.1342 |
Loa Loa (eye worm) | hypothetical protein | 0.0863 | 0.8848 | 0.8848 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0863 | 0.8848 | 0.8848 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0179 | 0.1117 | 0.379 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0102 | 0.0244 | 0.0244 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0102 | 0.0244 | 0.042 |
Brugia malayi | protein kinase C II. | 0.0179 | 0.1117 | 0.6138 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0341 | 0.2947 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0102 | 0.0244 | 0.042 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0102 | 0.0244 | 0.042 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0179 | 0.1117 | 0.1117 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0162 | 0.0922 | 0.3129 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0341 | 0.2947 | 1 |
Toxoplasma gondii | AGC kinase | 0.0102 | 0.0244 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0102 | 0.0244 | 0.0829 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0102 | 0.0244 | 0.0244 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0102 | 0.0244 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0091 | 0.0126 | 0.0427 |
Schistosoma mansoni | atypical protein kinase C | 0.0174 | 0.1059 | 0.3307 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0102 | 0.0244 | 0.0829 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0179 | 0.1117 | 0.379 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0269 | 0.2132 | 0.7236 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0102 | 0.0244 | 0.0244 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0102 | 0.0244 | 0.0829 |
Entamoeba histolytica | protein kinase, putative | 0.0102 | 0.0244 | 0.5 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0162 | 0.0922 | 0.3129 |
Echinococcus granulosus | protein kinase C gamma type | 0.0269 | 0.2132 | 0.7236 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0102 | 0.0244 | 0.0829 |
Echinococcus granulosus | protein kinase c iota type | 0.0174 | 0.1059 | 0.3593 |
Entamoeba histolytica | protein kinase, putative | 0.0102 | 0.0244 | 0.5 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0102 | 0.0244 | 0.0829 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Schistosoma mansoni | serine/threonine kinase | 0.0102 | 0.0244 | 0.042 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0102 | 0.0244 | 0.0829 |
Echinococcus multilocularis | protein kinase c iota type | 0.0174 | 0.1059 | 0.3593 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0169 | 0.1005 | 0.1005 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0102 | 0.0244 | 0.0244 |
Brugia malayi | Protein kinase domain containing protein | 0.0102 | 0.0244 | 0.1342 |
Loa Loa (eye worm) | hypothetical protein | 0.0935 | 0.9662 | 0.9662 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0102 | 0.0244 | 0.0244 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0341 | 0.2947 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0102 | 0.0244 | 0.1342 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0102 | 0.0244 | 0.0829 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1737 | 0.1737 |
Entamoeba histolytica | protein kinase, putative | 0.0102 | 0.0244 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0179 | 0.1117 | 0.3513 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0162 | 0.0922 | 0.3129 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0102 | 0.0244 | 0.0829 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0091 | 0.0126 | 0.0427 |
Entamoeba histolytica | protein kinase, putative | 0.0102 | 0.0244 | 0.5 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0102 | 0.0244 | 0.0244 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Brugia malayi | Protein kinase c protein 2 | 0.0241 | 0.182 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0102 | 0.0244 | 0.0829 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0102 | 0.0244 | 0.1342 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0091 | 0.0126 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0102 | 0.0244 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0091 | 0.0126 | 0.0427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.