Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.5444 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.03 | 1 | 1 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.015 | 0.3388 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0207 | 0.5912 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0207 | 0.5912 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.03 | 1 | 1 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0217 | 0.6347 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.5444 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0217 | 0.6347 | 0.1982 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0217 | 0.6347 | 0.6347 |
Echinococcus granulosus | geminin | 0.0197 | 0.5444 | 1 |
Onchocerca volvulus | 0.0217 | 0.6347 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.03 | 1 | 1 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0217 | 0.6347 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.03 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0197 | 0.5444 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0217 | 0.6347 | 0.1982 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0217 | 0.6347 | 0.5 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0217 | 0.6347 | 0.5 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0217 | 0.6347 | 0.1982 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0217 | 0.6347 | 0.1982 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0217 | 0.6347 | 0.6347 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.03 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0217 | 0.6347 | 0.1982 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0217 | 0.6347 | 0.1982 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.03 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.03 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.