Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0173 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0173 | 1 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0064 | 0.3446 | 0.339 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0173 | 1 | 1 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0009 | 0.0085 | 0.5 |
Plasmodium falciparum | ABC transporter G family member 2 | 0.0009 | 0.0085 | 0.5 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0064 | 0.3446 | 0.339 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.0009 | 0.0085 | 0.0085 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0173 | 1 | 1 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0173 | 1 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0064 | 0.3446 | 0.339 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0173 | 1 | 1 |
Schistosoma mansoni | ABC transporter | 0.0007 | 0.0006 | 0.0006 |
Mycobacterium tuberculosis | Probable conserved transmembrane ATP-binding protein ABC transporter | 0.0007 | 0 | 0.5 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0009 | 0.0085 | 0.5 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0173 | 1 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0173 | 1 | 1 |
Plasmodium vivax | ABC transporter G family member 2, putative | 0.0009 | 0.0085 | 0.5 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0064 | 0.3446 | 0.339 |
Entamoeba histolytica | ABC transporter, putative | 0.0009 | 0.0085 | 0.5 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0064 | 0.3446 | 0.339 |
Leishmania major | 0.0173 | 1 | 1 | |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0009 | 0.0085 | 0.5 |
Giardia lamblia | ABC transporter | 0.0009 | 0.0079 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.