Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0052 | 0.2731 | 0.5 | |
Onchocerca volvulus | 0.0052 | 0.2731 | 0.5 | |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0076 | 1 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0076 | 1 | 1 |
Schistosoma mansoni | amidase | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0076 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0076 | 1 | 1 |
Onchocerca volvulus | Subfamily M14A unassigned peptidase homolog | 0.0052 | 0.2731 | 0.5 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0076 | 1 | 1 |
Onchocerca volvulus | 0.0052 | 0.2731 | 0.5 | |
Onchocerca volvulus | 0.0052 | 0.2731 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
k obs / 1 (binding) | = 4900 M-1 s-1 | Inhibition of IL-1 beta converting enzyme | ChEMBL. | No reference |
k obs / 1 (binding) | = 4900 M-1 s-1 | Inhibition of IL-1 beta converting enzyme | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.