Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0191 | 0.0244 | 0.0657 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0187 | 0.0205 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0187 | 0.0205 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0284 | 0.1154 | 0.1133 |
Schistosoma mansoni | tyrosine kinase | 0.0284 | 0.1154 | 0.1133 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0171 | 0.0052 | 0.0028 |
Brugia malayi | Protein kinase domain containing protein | 0.0171 | 0.0052 | 0.0028 |
Schistosoma mansoni | histone deacetylase | 0.0187 | 0.0205 | 0.0181 |
Schistosoma mansoni | tyrosine kinase | 0.0284 | 0.1154 | 0.1133 |
Schistosoma mansoni | tyrosine kinase | 0.0287 | 0.1183 | 0.1162 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0187 | 0.0205 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0171 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0171 | 0.0052 | 0.0028 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0187 | 0.0205 | 0.0539 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0513 | 0.3373 | 0.3357 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0287 | 0.1183 | 0.1162 |
Echinococcus multilocularis | insulin receptor | 0.0171 | 0.0052 | 0.0052 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0535 | 0.3588 | 0.3572 |
Leishmania major | 0.0513 | 0.3373 | 1 | |
Schistosoma mansoni | tyrosine kinase | 0.0535 | 0.3588 | 0.3572 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0168 | 0.0024 | 0.0024 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0513 | 0.3373 | 0.3357 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Trypanosoma brucei | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.0205 | 0.0181 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0187 | 0.0205 | 0.0539 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0191 | 0.0244 | 0.0657 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0187 | 0.0205 | 0.0181 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0535 | 0.3588 | 0.3588 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0513 | 0.3373 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0535 | 0.3588 | 0.3572 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0187 | 0.0205 | 0.0539 |
Entamoeba histolytica | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Echinococcus granulosus | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0181 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1195 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0535 | 0.3588 | 0.3572 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0173 | 0.0071 | 0.0071 |
Echinococcus multilocularis | c Jun NH2 terminal kinase | 0.1195 | 1 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0513 | 0.3373 | 0.3357 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0181 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0513 | 0.3373 | 1 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0187 | 0.0205 | 0.0181 |
Loa Loa (eye worm) | CMGC/MAPK/JNK protein kinase | 0.1195 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0173 | 0.0071 | 0.0047 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0187 | 0.0205 | 0.0205 |
Echinococcus granulosus | histone deacetylase 3 | 0.0187 | 0.0205 | 0.0181 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0513 | 0.3373 | 0.3357 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0287 | 0.1183 | 0.1162 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0513 | 0.3373 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0287 | 0.1183 | 0.1183 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0168 | 0.0024 | 0.0024 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0191 | 0.0244 | 0.0657 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0187 | 0.0205 | 0.5 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0513 | 0.3373 | 0.3373 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0513 | 0.3373 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.0052 | 0.0028 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0191 | 0.0244 | 0.0657 |
Echinococcus granulosus | insulin receptor | 0.0171 | 0.0052 | 0.0028 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0187 | 0.0205 | 0.0539 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0187 | 0.0205 | 0.0539 |
Echinococcus multilocularis | histone deacetylase | 0.0168 | 0.0024 | 0.0024 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0205 |
Echinococcus granulosus | c-Jun N-terminal kinases | 0.1195 | 1 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0187 | 0.0205 | 0.0181 |
Brugia malayi | Histone deacetylase 1 | 0.0187 | 0.0205 | 0.0181 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.0052 | 0.0028 |
Schistosoma mansoni | histone deacetylase | 0.0187 | 0.0205 | 0.0181 |
Giardia lamblia | Histone deacetylase | 0.0187 | 0.0205 | 0.5 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0191 | 0.0244 | 0.0657 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0168 | 0.0024 | 0.0024 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0173 | 0.0071 | 0.0047 |
Leishmania major | histone deacetylase, putative | 0.0187 | 0.0205 | 0.0539 |
Schistosoma mansoni | tyrosine kinase | 0.0287 | 0.1183 | 0.1162 |
Plasmodium falciparum | histone deacetylase 1 | 0.0187 | 0.0205 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.