Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone deacetylase | 0.0168 | 0.0024 | 0.0024 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0187 | 0.0205 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0187 | 0.0205 | 0.0539 |
Leishmania major | 0.0513 | 0.3373 | 1 | |
Brugia malayi | Histone deacetylase 1 | 0.0187 | 0.0205 | 0.0181 |
Trypanosoma brucei | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0539 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0191 | 0.0244 | 0.0657 |
Schistosoma mansoni | tyrosine kinase | 0.0284 | 0.1154 | 0.1133 |
Echinococcus multilocularis | insulin receptor | 0.0171 | 0.0052 | 0.0052 |
Echinococcus granulosus | histone deacetylase 3 | 0.0187 | 0.0205 | 0.0181 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0171 | 0.0052 | 0.0052 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0513 | 0.3373 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0187 | 0.0205 | 0.0181 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0187 | 0.0205 | 0.0539 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0187 | 0.0205 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0284 | 0.1154 | 0.1133 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0187 | 0.0205 | 0.0181 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.0052 | 0.0028 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0513 | 0.3373 | 0.3357 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0187 | 0.0205 | 0.0181 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0191 | 0.0244 | 0.0657 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0187 | 0.0205 | 0.0539 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0287 | 0.1183 | 0.1162 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0535 | 0.3588 | 0.3572 |
Echinococcus granulosus | histone deacetylase 6 | 0.0173 | 0.0071 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.0205 | 0.0181 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0187 | 0.0205 | 0.0181 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0187 | 0.0205 | 0.0539 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0187 | 0.0205 | 0.0539 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0187 | 0.0205 | 0.0205 |
Entamoeba histolytica | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1195 | 1 | 1 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0513 | 0.3373 | 0.3373 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0173 | 0.0071 | 0.0071 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0168 | 0.0024 | 0.0024 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0168 | 0.0024 | 0.0024 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0513 | 0.3373 | 0.3357 |
Schistosoma mansoni | tyrosine kinase | 0.0284 | 0.1154 | 0.1133 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0513 | 0.3373 | 1 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0191 | 0.0244 | 0.0657 |
Echinococcus granulosus | c-Jun N-terminal kinases | 0.1195 | 1 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0513 | 0.3373 | 0.3357 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0187 | 0.0205 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0181 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0287 | 0.1183 | 0.1162 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0513 | 0.3373 | 0.3357 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0173 | 0.0071 | 0.0047 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0513 | 0.3373 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0187 | 0.0205 | 0.0181 |
Echinococcus granulosus | insulin receptor | 0.0171 | 0.0052 | 0.0028 |
Echinococcus multilocularis | c Jun NH2 terminal kinase | 0.1195 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.0052 | 0.0028 |
Giardia lamblia | Histone deacetylase | 0.0187 | 0.0205 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0287 | 0.1183 | 0.1183 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0187 | 0.0205 | 0.5 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0171 | 0.0052 | 0.0028 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0287 | 0.1183 | 0.1162 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0191 | 0.0244 | 0.0657 |
Brugia malayi | Protein kinase domain containing protein | 0.0171 | 0.0052 | 0.0028 |
Schistosoma mansoni | tyrosine kinase | 0.0287 | 0.1183 | 0.1162 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0205 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0535 | 0.3588 | 0.3572 |
Schistosoma mansoni | tyrosine kinase | 0.0535 | 0.3588 | 0.3572 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0535 | 0.3588 | 0.3572 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0535 | 0.3588 | 0.3588 |
Loa Loa (eye worm) | CMGC/MAPK/JNK protein kinase | 0.1195 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.0187 | 0.0205 | 0.0539 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0191 | 0.0244 | 0.0657 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0168 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0171 | 0.0052 | 0.0028 |
Plasmodium falciparum | histone deacetylase 1 | 0.0187 | 0.0205 | 1 |
Echinococcus granulosus | histone deacetylase 1 | 0.0187 | 0.0205 | 0.0181 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0513 | 0.3373 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0187 | 0.0205 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.