Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0104 | 0.3372 | 0.0909 |
Echinococcus granulosus | nervana 2 | 0.0199 | 0.6544 | 0.9791 |
Toxoplasma gondii | AGC kinase | 0.0303 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0199 | 0.6544 | 0.9791 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0104 | 0.3372 | 0.0467 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0096 | 0.3122 | 0.0209 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0201 | 0.6619 | 1 |
Entamoeba histolytica | protein kinase 2, putative | 0.0201 | 0.6619 | 0.4899 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0104 | 0.3372 | 0.0467 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0201 | 0.6619 | 1 |
Brugia malayi | protein kinase C II. | 0.0104 | 0.3372 | 0.0467 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0104 | 0.3372 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.3372 | 0.0467 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0201 | 0.6619 | 0.4899 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0094 | 0.3056 | 0.0026 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0104 | 0.3372 | 0.0909 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0201 | 0.6619 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0303 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0104 | 0.3372 | 0.0467 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0094 | 0.3056 | 0.0026 |
Trichomonas vaginalis | AGC family protein kinase | 0.0104 | 0.3372 | 0.0467 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Echinococcus granulosus | calcium activated potassium channel | 0.0096 | 0.3122 | 0.0209 |
Schistosoma mansoni | transient receptor potential channel | 0.0094 | 0.3047 | 0.0000043397 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0094 | 0.3047 | 0.0000043397 |
Entamoeba histolytica | protein kinase, putative | 0.0303 | 1 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0094 | 0.3047 | 0.5 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0199 | 0.6544 | 0.9791 |
Trichomonas vaginalis | AGC family protein kinase | 0.0104 | 0.3372 | 0.0467 |
Brugia malayi | Protein kinase domain containing protein | 0.0104 | 0.3372 | 0.0467 |
Echinococcus multilocularis | nervana 2 | 0.0199 | 0.6544 | 0.9791 |
Echinococcus granulosus | protein kinase C gamma type | 0.0104 | 0.3372 | 0.0909 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0094 | 0.3047 | 0.0000043397 |
Entamoeba histolytica | protein kinase, putative | 0.0303 | 1 | 1 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0201 | 0.6619 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.3056 | 0.0013 |
Echinococcus multilocularis | protein kinase c iota type | 0.0104 | 0.3372 | 0.0909 |
Schistosoma mansoni | serine/threonine kinase | 0.0104 | 0.3372 | 0.0909 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0094 | 0.3047 | 0.0000043397 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0104 | 0.3372 | 0.0909 |
Trichomonas vaginalis | AGC family protein kinase | 0.0104 | 0.3372 | 0.0467 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0201 | 0.6619 | 1 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0102 | 0.3297 | 0.036 |
Schistosoma mansoni | atypical protein kinase C | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0201 | 0.6619 | 1 |
Onchocerca volvulus | 0.0094 | 0.3047 | 0.5 | |
Brugia malayi | Protein kinase domain containing protein | 0.0303 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0094 | 0.3056 | 0.0026 |
Echinococcus granulosus | nervana 2 | 0.0199 | 0.6544 | 0.9791 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0201 | 0.6619 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0104 | 0.3372 | 0.0909 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0094 | 0.3056 | 0.0026 |
Leishmania major | hypothetical protein, unknown function | 0.0094 | 0.3047 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0199 | 0.6544 | 0.9791 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Brugia malayi | olfactory channel protein osm-9 | 0.0094 | 0.3056 | 0.0013 |
Schistosoma mansoni | transient receptor potential channel | 0.0094 | 0.3056 | 0.0026 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0199 | 0.6544 | 0.9791 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0104 | 0.3372 | 0.0909 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0303 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.3047 | 0.0000022294 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0201 | 0.6619 | 1 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0201 | 0.6619 | 0.5 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0303 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0104 | 0.3372 | 0.0467 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0104 | 0.3372 | 0.0909 |
Entamoeba histolytica | protein kinase, putative | 0.0303 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Echinococcus multilocularis | nervana 2 | 0.0199 | 0.6544 | 0.9791 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0104 | 0.3372 | 0.0909 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0104 | 0.3372 | 0.0467 |
Brugia malayi | Hr1 repeat family protein | 0.0104 | 0.3372 | 0.0467 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0104 | 0.3372 | 0.0467 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0201 | 0.6619 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0104 | 0.3372 | 0.0909 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.3047 | 0.0000022294 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0201 | 0.6619 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0094 | 0.3056 | 0.0026 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0094 | 0.3047 | 0.5 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0104 | 0.3372 | 0.0909 |
Trichomonas vaginalis | AGC family protein kinase | 0.0303 | 1 | 1 |
Trypanosoma cruzi | Protein kinase B | 0.0201 | 0.6619 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0104 | 0.3372 | 0.0909 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0201 | 0.6619 | 0.4899 |
Schistosoma mansoni | transient receptor potential channel | 0.0094 | 0.3047 | 0.0000043397 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0094 | 0.3047 | 0.5 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0094 | 0.3047 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.3372 | 0.0909 |
Giardia lamblia | Kinase, AGC PKA | 0.0201 | 0.6619 | 1 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0104 | 0.3372 | 0.0909 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0104 | 0.3372 | 0.0467 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0104 | 0.3372 | 0.0909 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.