Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | licC protein (licC) | 0.0122 | 0.0574 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.1033 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0663 | 0.6172 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0066 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0066 | 0 | 0.5 |
Mycobacterium leprae | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.0663 | 0.6172 | 0.5 |
Brugia malayi | serine/threonine kinase 12 | 0.0066 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0 | 0.5 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0066 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0 | 0.5 |
Trypanosoma brucei | aurora B kinase | 0.0066 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0066 | 0 | 0.5 |
Entamoeba histolytica | protein kinase , putative | 0.0066 | 0 | 0.5 |
Mycobacterium ulcerans | bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase | 0.0663 | 0.6172 | 1 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.0663 | 0.6172 | 1 |
Toxoplasma gondii | eukaryotic initiation factor-2B, gamma subunit, putative | 0.0122 | 0.0574 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0 | 0.5 |
Giardia lamblia | Aurora kinase | 0.0066 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0066 | 0 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0066 | 0 | 0.5 |
Leishmania major | protein kinase, putative | 0.0066 | 0 | 0.5 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0066 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0066 | 0 | 0.5 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0066 | 0 | 0.5 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0066 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0 | 0.5 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0066 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.