Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | SET domain protein, putative | 0.0385 | 0.5 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET8 | 0.0385 | 0.5 | 0.5 |
Echinococcus granulosus | histone lysine n methyltransferase setd8 | 0.0385 | 0.5 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase seto7 | 0.0385 | 0.5 | 0.5 |
Echinococcus multilocularis | histone lysine n methyltransferase setd8 | 0.0385 | 0.5 | 0.5 |
Plasmodium falciparum | SET domain protein, putative | 0.0385 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.