Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.0525 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0417 | 0.6888 | 0.6888 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0349 | 0.4899 | 0.7112 |
Echinococcus granulosus | nervana 2 | 0.0345 | 0.4787 | 0.6949 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0525 | 1 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0349 | 0.4899 | 0.5 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0525 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0345 | 0.4787 | 0.6949 |
Echinococcus granulosus | histone lysine n methyltransferase setd8 | 0.0417 | 0.6888 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0349 | 0.4899 | 0.7112 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0349 | 0.4899 | 0.5 |
Giardia lamblia | Kinase, AGC PKA | 0.0349 | 0.4899 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0525 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0345 | 0.4787 | 0.6949 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0345 | 0.4787 | 0.6949 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0349 | 0.4899 | 0.7112 |
Plasmodium vivax | SET domain protein, putative | 0.0417 | 0.6888 | 1 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0345 | 0.4787 | 0.6949 |
Brugia malayi | Protein set-1 | 0.0417 | 0.6888 | 0.6888 |
Brugia malayi | Protein kinase domain containing protein | 0.0525 | 1 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0345 | 0.4787 | 0.6949 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0349 | 0.4899 | 0.4899 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0349 | 0.4899 | 0.7112 |
Schistosoma mansoni | histone-lysine n-methyltransferase seto7 | 0.0417 | 0.6888 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0345 | 0.4787 | 0.6949 |
Plasmodium falciparum | SET domain protein, putative | 0.0417 | 0.6888 | 1 |
Echinococcus granulosus | nervana 2 | 0.0345 | 0.4787 | 0.6949 |
Toxoplasma gondii | AGC kinase | 0.0525 | 1 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0349 | 0.4899 | 0.7112 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0349 | 0.4899 | 0.7112 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0525 | 1 | 0.5 |
Echinococcus multilocularis | histone lysine n methyltransferase setd8 | 0.0417 | 0.6888 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0349 | 0.4899 | 0.4899 |
Trichomonas vaginalis | AGC family protein kinase | 0.0525 | 1 | 1 |
Trypanosoma cruzi | Protein kinase B | 0.0349 | 0.4899 | 0.5 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0349 | 0.4899 | 0.7112 |
Entamoeba histolytica | protein kinase 2, putative | 0.0349 | 0.4899 | 0.4899 |
Entamoeba histolytica | protein kinase, putative | 0.0525 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Binding affinity to Laodelphax striatella (small brown planthopper) nicotinic acetylcholine receptor | ChEMBL. | 20919736 | |
Activity (binding) | Binding affinity to Nephotettix cincticeps (green rice leafhopper) nicotinic acetylcholine receptor | ChEMBL. | 20919736 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.