Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | protoporphyrinogen oxidase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | Putative uncharacterized protein ML2045 | 0.0229 | 1 | 1 |
Loa Loa (eye worm) | alpha amylase | 0.0229 | 1 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0229 | 1 | 1 |
Echinococcus granulosus | alpha glucosidase | 0.0229 | 1 | 1 |
Brugia malayi | Alpha amylase, catalytic domain containing protein | 0.0229 | 1 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0229 | 1 | 1 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0192 | 0.4021 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0229 | 1 | 1 |
Mycobacterium tuberculosis | Trehalose synthase TreS | 0.0229 | 1 | 1 |
Loa Loa (eye worm) | alpha amylase | 0.0229 | 1 | 0.5 |
Mycobacterium ulcerans | trehalose synthase TreS | 0.0229 | 1 | 1 |
Mycobacterium tuberculosis | Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas | 0.0229 | 1 | 1 |
Schistosoma mansoni | alpha-amylase | 0.0229 | 1 | 1 |
Schistosoma mansoni | alpha-amylase | 0.0229 | 1 | 1 |
Echinococcus multilocularis | alpha glucosidase | 0.0229 | 1 | 1 |
Entamoeba histolytica | oligo-1,6-glucosidase, putative | 0.0229 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.