TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 473.525 | Formula: C23H28N3O4PS
H donors: 2 H acceptors: 3 LogP: 4.07 Rotable bonds: 13
Rule of 5 violations (Lipinski): 1
SMILES: CCOP(=O)(C(c1ccccc1)N/C(=C(\C(=O)NCc1ccccc1)/C#N)/SC)OCC
InChi: 1S/C23H28N3O4PS/c1-4-29-31(28,30-5-2)22(19-14-10-7-11-15-19)26-23(32-3)20(16-24)21(27)25-17-18-12-8-6-9-13-18/h6-15,22,26H,4-5,17H2,1-3H3,(H,25,27)/b23-20+
InChiKey: WQDDCCUIZYQFCX-BSYVCWPDSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	neuropeptide s receptor	0.0603	0.7234	0.7234
Schistosoma mansoni	hypothetical protein	0.0145	0.1086	0.1086
Trypanosoma cruzi	serine peptidase, Clan SC, Family S10, putative	0.0809	1	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0145	0.1086	0.1086
Schistosoma mansoni	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	fmrfamide receptor	0.0145	0.1086	0.1086
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Echinococcus multilocularis	neuropeptide receptor A26	0.0603	0.7234	0.7234
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0145	0.1086	0.1086
Brugia malayi	sulfakinin receptor protein	0.0145	0.1086	0.1086
Schistosoma mansoni	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.008	0.0204	0.0204
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0145	0.1086	0.1086
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0145	0.1086	0.1086
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptide Y receptor	0.0145	0.1086	0.1086
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Schistosoma mansoni	lysosomal protective protein precursor (cathepsin A) (carboxypeptidase	0.008	0.0206	0.0206
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	Melatonin receptor type 1A	0.0145	0.1086	0.1086
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0145	0.1086	0.1086
Schistosoma mansoni	opsin-like receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptides capa receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0145	0.1086	0.1086
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	larval opioid receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0145	0.1086	0.1086
Loa Loa (eye worm)	G-protein coupled receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	tm gpcr rhodopsin	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	TYRA-2 protein	0.0145	0.1086	0.1086
Echinococcus granulosus	serotonin receptor	0.0145	0.1086	0.1086
Brugia malayi	G protein-coupled receptor F59B2.13	0.0145	0.1086	0.1086
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	amine GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptides capa receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	melatonin receptor type 1A	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	serotonin receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	geminin	0.0187	0.1645	0.1645
Echinococcus granulosus	biogenic amine 5HT receptor	0.0145	0.1086	0.1086
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Trypanosoma cruzi	serine carboxypeptidase (CBP1), putative	0.0809	1	0.5
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	hypothetical protein	0.0187	0.1645	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	peptidase Clp (S14 family)	0.008	0.0204	0.0204
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0145	0.1086	0.1086
Schistosoma mansoni	myosin xvIII	0.0145	0.1086	0.1086
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	7TM GPCR rhodopsin	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0145	0.1086	0.1086
Brugia malayi	Serotonin receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0145	0.1086	0.1086
Schistosoma mansoni	opsin-like receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	dro:myosuppressin receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	opsin-like receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0145	0.1086	0.1086
Brugia malayi	Probable ClpP-like protease	0.008	0.0204	0.0204
Echinococcus multilocularis	orexin receptor type 2	0.0145	0.1086	0.1086
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	biogenic amine 5HT receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	G protein-coupled receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	neuropeptides capa receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0145	0.1086	0.1086
Echinococcus granulosus	allatostatin A receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0145	0.1086	0.1086
Brugia malayi	GnHR receptor homolog	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	g-protein coupled receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Brugia malayi	putative neuropeptide receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0145	0.1086	0.1086
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.008	0.0204	0.5
Echinococcus granulosus	g protein coupled receptor	0.0145	0.1086	0.1086
Brugia malayi	ORL1-like opioid receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptide receptor	0.0145	0.1086	0.1086
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide receptor	0.0145	0.1086	0.1086
Brugia malayi	Dopamine receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	dro:myosuppressin receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.012	0.0748	0.0748
Echinococcus granulosus	neuropeptide receptor	0.0145	0.1086	0.1086
Trypanosoma brucei	serine peptidase, Clan SC, Family S10	0.0809	1	0.5
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	neuropeptide Y receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0145	0.1086	0.1086
Trypanosoma brucei	serine peptidase, Clan SC, Family S10	0.0809	1	0.5
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	neuropeptide Y receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0145	0.1086	0.1086
Trypanosoma brucei	serine peptidase, Clan SC, Family S10	0.0809	1	0.5
Echinococcus multilocularis	somatostatin receptor	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	follicle stimulating hormone receptor	0.0145	0.1086	0.1086
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide f receptor 76f	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0145	0.1086	0.1086
Brugia malayi	AKH receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0145	0.1086	0.1086
Leishmania major	serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10	0.0809	1	0.5
Schistosoma mansoni	lipoxygenase	0.0084	0.0262	0.0262
Brugia malayi	G-protein coupled receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	amine GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	MH2 domain-containing protein	0.0117	0.0707	0.0707
Echinococcus multilocularis	neuropeptide receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.012	0.0748	0.0748
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	Dopamine receptor protein 1	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.008	0.0204	0.5
Schistosoma mansoni	lipoxygenase	0.012	0.0748	0.0748
Brugia malayi	neuropeptide F receptor	0.0145	0.1086	0.1086
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	family S10 non peptidase ue S10 family	0.0729	0.8926	0.8926
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine receptor	0.0145	0.1086	0.1086
Trypanosoma cruzi	serine carboxypeptidase (CBP1), putative	0.0809	1	0.5
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0145	0.1086	0.1086
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Echinococcus granulosus	7tm_1 domain containing protein	0.0145	0.1086	0.1086
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.008	0.0204	0.5
Loa Loa (eye worm)	hypothetical protein	0.0809	1	1
Echinococcus granulosus	somatostatin receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0145	0.1086	0.1086
Trypanosoma cruzi	serine peptidase, Clan SC, Family S10, putative	0.0809	1	0.5
Echinococcus granulosus	lysosomal protective protein	0.0809	1	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	family S10 non-peptidase homologue (S10 family)	0.0809	1	1
Echinococcus granulosus	geminin	0.0187	0.1645	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide F-like receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	fmrfamide receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	g protein coupled receptor	0.0145	0.1086	0.1086
Onchocerca volvulus	Uncharacterized serine carboxypeptidase homolog	0.0809	1	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	RE15519p	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Brugia malayi	neuropeptide F receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0145	0.1086	0.1086
Brugia malayi	MH2 domain containing protein	0.0117	0.0707	0.0707
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	sex peptide receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	adenoreceptor	0.0145	0.1086	0.1086
Echinococcus granulosus	tm gpcr rhodopsin	0.0145	0.1086	0.1086
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0145	0.1086	0.1086
Echinococcus granulosus	G protein coupled receptor 139	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptide FF receptor 2	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	neuropeptide F receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	family S10 unassigned peptidase (S10 family)	0.0809	1	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	hypothetical protein	0.0187	0.1645	0.1645
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	histamine h1 receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	G-protein coupled receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	tm gpcr rhodopsin	0.0145	0.1086	0.1086
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.008	0.0204	0.0204
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0145	0.1086	0.1086
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.008	0.0204	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptide s receptor	0.0603	0.7234	0.7234
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Echinococcus multilocularis	neuropeptides capa receptor	0.0145	0.1086	0.1086
Brugia malayi	Serotonin receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	g protein coupled receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.008	0.0204	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Echinococcus granulosus	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	fmrfamide receptor	0.0145	0.1086	0.1086
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.008	0.0204	0.5
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	neuropeptide F-like receptor	0.0145	0.1086	0.1086
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0145	0.1086	0.1086
Echinococcus granulosus	neuropeptide Y receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	orexin receptor type 2	0.0145	0.1086	0.1086
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	g-protein coupled receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	lysosomal protective protein	0.0809	1	1
Echinococcus granulosus	neuropeptide receptor A26	0.0603	0.7234	0.7234
Schistosoma mansoni	hypothetical protein	0.0145	0.1086	0.1086
Brugia malayi	Dopamine receptor protein 2	0.0145	0.1086	0.1086
Echinococcus multilocularis	family S10 non peptidase ue (S10 family)	0.0729	0.8926	0.8926
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	amine GPCR	0.0145	0.1086	0.1086
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus multilocularis	g protein coupled receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	amine GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Schistosoma mansoni	amine GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	transcription factor SMAD2	0.0117	0.0707	0.0707
Brugia malayi	G-protein coupled receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	g protein coupled receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	growth hormone secretagogue receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Echinococcus multilocularis	neuropeptide receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	sex peptide receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	serotonin receptor	0.0145	0.1086	0.1086
Echinococcus granulosus	g protein coupled receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1086	0.1086
Echinococcus granulosus	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	G protein coupled receptor 139	0.0145	0.1086	0.1086
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0145	0.1086	0.1086
Schistosoma mansoni	biogenic amine receptor	0.0145	0.1086	0.1086
Brugia malayi	putative neuropeptide receptor NPR1	0.0145	0.1086	0.1086
Echinococcus multilocularis	allatostatin A receptor	0.0145	0.1086	0.1086
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0145	0.1086	0.1086
Brugia malayi	hypothetical protein	0.0145	0.1086	0.1086

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2228209

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1812578