Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.2397 | 0.8528 | 0.9113 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.054 | 0.0781 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2397 | 0.8528 | 0.9113 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.054 | 0.0781 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.2397 | 0.8528 | 0.9113 |
Loa Loa (eye worm) | hypothetical protein | 0.2596 | 0.9358 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.054 | 0.0781 | 1 |
Onchocerca volvulus | 0.255 | 0.917 | 0.5 | |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.054 | 0.0781 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.