Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | protein kinase | 0.0105 | 0.1349 | 0.8764 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0111 | 0.1539 | 0.5 |
Echinococcus multilocularis | aurora kinase A | 0.0111 | 0.1539 | 0.189 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0102 | 0.1284 | 0.8276 |
Loa Loa (eye worm) | AUR protein kinase | 0.0111 | 0.1539 | 0.1539 |
Trichomonas vaginalis | STE family protein kinase | 0.0105 | 0.1349 | 0.8711 |
Toxoplasma gondii | aurora kinase | 0.0111 | 0.1539 | 0.5 |
Giardia lamblia | Aurora kinase | 0.0111 | 0.1539 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0105 | 0.1349 | 0.1656 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0063 | 0.0064 | 0.0079 |
Loa Loa (eye worm) | AUR protein kinase | 0.0111 | 0.1539 | 0.1539 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0064 | 0.0416 |
Loa Loa (eye worm) | AUR protein kinase | 0.0111 | 0.1539 | 0.1539 |
Entamoeba histolytica | p21-activated kinase | 0.0105 | 0.1349 | 0.8764 |
Entamoeba histolytica | protein kinase, putative | 0.0105 | 0.1349 | 0.8764 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0105 | 0.1349 | 0.1656 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0064 | 0.0416 |
Brugia malayi | serine/threonine kinase 12 | 0.0111 | 0.1539 | 0.1539 |
Brugia malayi | Protein kinase domain | 0.0105 | 0.1349 | 0.1349 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0111 | 0.1539 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0105 | 0.1349 | 0.8711 |
Leishmania major | protein kinase, putative | 0.0111 | 0.1539 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0111 | 0.1539 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0064 | 0.0416 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0111 | 0.1539 | 0.1539 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0105 | 0.1349 | 0.1656 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0111 | 0.1539 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0111 | 0.1539 | 1 |
Loa Loa (eye worm) | STE/STE20/PAKB protein kinase | 0.0387 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0111 | 0.1539 | 1 |
Trypanosoma brucei | aurora B kinase | 0.0111 | 0.1539 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.0326 | 0.8142 | 1 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0111 | 0.1539 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0111 | 0.1539 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.0111 | 0.1539 | 1 |
Echinococcus granulosus | aurora kinase A | 0.0111 | 0.1539 | 0.189 |
Trichomonas vaginalis | AGC family protein kinase | 0.0111 | 0.1539 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1284 | 0.1284 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0111 | 0.1539 | 0.189 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0111 | 0.1539 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0105 | 0.1349 | 0.1656 |
Schistosoma mansoni | protein kinase | 0.0063 | 0.0064 | 0.0416 |
Trichomonas vaginalis | STE family protein kinase | 0.0105 | 0.1349 | 0.8711 |
Trichomonas vaginalis | AGC family protein kinase | 0.0111 | 0.1539 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0111 | 0.1539 | 0.1539 |
Trichomonas vaginalis | STE family protein kinase | 0.0105 | 0.1349 | 0.8711 |
Schistosoma mansoni | protein kinase | 0.0105 | 0.1349 | 0.8764 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0105 | 0.1349 | 0.1656 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0111 | 0.1539 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0111 | 0.1539 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.0326 | 0.8142 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0111 | 0.1539 | 0.189 |
Entamoeba histolytica | protein kinase, putative | 0.0111 | 0.1539 | 1 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0105 | 0.1349 | 0.1656 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0111 | 0.1539 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Change (functional) | = 0 % | Peak percent change in contractile force produced by the administration of 1 mg/kg intravenously in anesthetized dog | ChEMBL. | 2153209 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.