Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | calcium-gated potassium channel protein, putative | 0.2415 | 0.0437 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 2.118 | 0.5195 | 1 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.2415 | 0.0437 | 0.5 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Brugia malayi | Protein kinase domain containing protein | 2.118 | 0.5195 | 0.4976 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 2.118 | 0.5195 | 0.4976 |
Echinococcus granulosus | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Mycobacterium ulcerans | transmembrane cation transporter | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | TWiK family of potassium channels protein 7 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 2.118 | 0.5195 | 0.5195 |
Echinococcus multilocularis | sodium channel protein | 0.9685 | 0.228 | 0.228 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.2415 | 0.0437 | 0.0437 |
Mycobacterium ulcerans | ion transport protein | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.2415 | 0.0437 | 0.0437 |
Echinococcus granulosus | potassium channel subfamily K | 0.2415 | 0.0437 | 0.0437 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 3.7712 | 0.9388 | 0.936 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 4.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 4.0127 | 1 | 1 |
Plasmodium vivax | potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Trypanosoma cruzi | ion transport protein, putative | 0.2415 | 0.0437 | 0.5 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.9685 | 0.228 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 2.118 | 0.5195 | 0.4976 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.2415 | 0.0437 | 0.0437 |
Toxoplasma gondii | ion channel protein | 0.2415 | 0.0437 | 0.5 |
Mycobacterium tuberculosis | Possible transmembrane cation transporter | 0.2415 | 0.0437 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.9685 | 0.228 | 0.228 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.2415 | 0.0437 | 0.5 |
Plasmodium vivax | potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Trypanosoma brucei | calcium-activated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.2415 | 0.0437 | 0.5 |
Trypanosoma brucei | calcium/potassium channel (CAKC), putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.2415 | 0.0437 | 0.5 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 2.118 | 0.5195 | 0.4976 |
Plasmodium falciparum | potassium channel | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | sodium channel protein | 0.9685 | 0.228 | 0.228 |
Echinococcus multilocularis | TWiK family of potassium channels protein 7 | 0.2415 | 0.0437 | 0.0437 |
Schistosoma mansoni | twik family of potassium channels-related | 4.0127 | 1 | 1 |
Toxoplasma gondii | ion channel protein | 0.2415 | 0.0437 | 0.5 |
Trypanosoma cruzi | ion transport protein, putative | 0.2415 | 0.0437 | 0.5 |
Plasmodium falciparum | potassium channel | 0.2415 | 0.0437 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 2.118 | 0.5195 | 0.4976 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 2.118 | 0.5195 | 0.5195 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 4.0127 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 4.0127 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | potassium channel subfamily K | 0.2415 | 0.0437 | 0.0437 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.