Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Toxoplasma gondii | ion channel protein | 0.2415 | 0.0437 | 0.5 |
Mycobacterium ulcerans | transmembrane cation transporter | 0.2415 | 0.0437 | 0.5 |
Trypanosoma cruzi | ion transport protein, putative | 0.2415 | 0.0437 | 0.5 |
Toxoplasma gondii | ion channel protein | 0.2415 | 0.0437 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.2415 | 0.0437 | 0.5 |
Plasmodium falciparum | potassium channel | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus granulosus | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.9685 | 0.228 | 0.228 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.9685 | 0.228 | 1 |
Echinococcus granulosus | sodium channel protein | 0.9685 | 0.228 | 0.228 |
Schistosoma mansoni | twik family of potassium channels-related | 4.0127 | 1 | 1 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Trypanosoma brucei | calcium-activated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.2415 | 0.0437 | 0.0437 |
Plasmodium falciparum | potassium channel | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | sodium channel protein | 0.9685 | 0.228 | 0.228 |
Echinococcus granulosus | potassium channel subfamily K | 0.2415 | 0.0437 | 0.0437 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 2.118 | 0.5195 | 0.4976 |
Trypanosoma brucei | calcium/potassium channel (CAKC), putative | 0.2415 | 0.0437 | 0.5 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 2.118 | 0.5195 | 0.4976 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Mycobacterium tuberculosis | Possible transmembrane cation transporter | 0.2415 | 0.0437 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 2.118 | 0.5195 | 0.4976 |
Loa Loa (eye worm) | hypothetical protein | 4.0127 | 1 | 1 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | potassium channel subfamily K | 0.2415 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 4.0127 | 1 | 1 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | twik family of potassium channels | 0.2415 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 3.7712 | 0.9388 | 0.936 |
Echinococcus multilocularis | TWiK family of potassium channels protein 7 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.2415 | 0.0437 | 0.0437 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 2.118 | 0.5195 | 0.4976 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 2.118 | 0.5195 | 1 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.2415 | 0.0437 | 0.0437 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.2415 | 0.0437 | 0.0437 |
Plasmodium vivax | potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Entamoeba histolytica | calcium-gated potassium channel protein, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 4.0127 | 1 | 1 |
Echinococcus granulosus | TWiK family of potassium channels protein 7 | 0.2415 | 0.0437 | 0.0437 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 4.0127 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.2415 | 0.0437 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 2.118 | 0.5195 | 0.5195 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.2415 | 0.0437 | 0.0437 |
Trypanosoma cruzi | ion transport protein, putative | 0.2415 | 0.0437 | 0.5 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 2.118 | 0.5195 | 0.5195 |
Mycobacterium ulcerans | ion transport protein | 0.2415 | 0.0437 | 0.5 |
Plasmodium vivax | potassium channel, putative | 0.2415 | 0.0437 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 2.118 | 0.5195 | 0.4976 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.