Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | SNF1-related protein kinase regulatory subunit beta, putative | 0.0111 | 0.1437 | 0.5 |
Echinococcus granulosus | AMPK beta subunit | 0.0111 | 0.1437 | 0.1838 |
Loa Loa (eye worm) | CAMK/CAMKL/AMPK protein kinase | 0.0233 | 0.4842 | 0.3976 |
Echinococcus multilocularis | 5' AMP activated protein kinase catalytic | 0.0233 | 0.4842 | 0.6192 |
Trypanosoma brucei | 5'-AMP-activated protein kinase subunit beta | 0.0111 | 0.1437 | 0.5 |
Echinococcus granulosus | 5' AMP activated protein kinase catalytic | 0.0233 | 0.4842 | 0.6192 |
Echinococcus granulosus | 5' AMP activated protein kinase subunit gamma | 0.034 | 0.782 | 1 |
Echinococcus multilocularis | 5' AMP activated protein kinase subunit gamma | 0.034 | 0.782 | 1 |
Echinococcus multilocularis | 5' AMP activated protein kinase subunit gamma | 0.0312 | 0.7053 | 0.9019 |
Leishmania major | hypothetical protein, conserved | 0.0111 | 0.1437 | 0.5 |
Loa Loa (eye worm) | loechrig isoform VII | 0.034 | 0.782 | 0.7454 |
Onchocerca volvulus | Alicorn homolog | 0.0097 | 0.1045 | 0.5 |
Toxoplasma gondii | 5'-AMP-activated protein kinase subunit beta-1 family protein, putative | 0.0066 | 0.0166 | 0.5 |
Giardia lamblia | 5-AMP-activated protein kinase, gamma-1 subunit | 0.034 | 0.782 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.9691 | 0.964 |
Brugia malayi | EST embl|AI107989|AI107989 comes from the 3' UTR, putative | 0.0233 | 0.4842 | 0.3976 |
Trypanosoma cruzi | 5'-AMP-activated protein kinase subunit beta, putative | 0.0111 | 0.1437 | 0.5 |
Echinococcus multilocularis | AMPK beta subunit | 0.0111 | 0.1437 | 0.1838 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0233 | 0.4842 | 0.6192 |
Schistosoma mansoni | protein kinase subunit gamma | 0.034 | 0.782 | 1 |
Schistosoma mansoni | protein kinase subunit beta | 0.0111 | 0.1437 | 0.1838 |
Brugia malayi | loechrig isoform VII | 0.034 | 0.782 | 0.7454 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.