TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 300.223 | Formula: C15H19Cl2NO
H donors: 0 H acceptors: 1 LogP: 3.99 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CCCN(C(=O)/C=C/C(Cl)C)Cc1ccc(cc1)Cl
InChi: 1S/C15H19Cl2NO/c1-3-10-18(15(19)9-4-12(2)16)11-13-5-7-14(17)8-6-13/h4-9,12H,3,10-11H2,1-2H3/b9-4+
InChiKey: JQAUEGBGUFKVOY-RUDMXATFSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	amine GPCR	0.006	0.1509	0.1509
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Brugia malayi	Serotonin receptor	0.006	0.1509	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.006	0.1509	0.1509
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	TKL/LRRK protein kinase	0.0057	0.1419	0.9408
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	adenoreceptor	0.006	0.1509	0.1509
Brugia malayi	G protein-coupled receptor F59B2.13	0.006	0.1509	1
Brugia malayi	GnHR receptor homolog	0.006	0.1509	1
Schistosoma mansoni	histamine h1 receptor	0.006	0.1509	0.1509
Echinococcus granulosus	tm gpcr rhodopsin	0.006	0.1509	0.1739
Echinococcus multilocularis	allatostatin A receptor	0.006	0.1509	0.1509
Schistosoma mansoni	myosin xvIII	0.006	0.1509	0.1509
Echinococcus multilocularis	neuropeptide Y receptor	0.006	0.1509	0.1509
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0051	0.1261	0.1453
Echinococcus granulosus	neuropeptide s receptor	0.006	0.1509	0.1739
Entamoeba histolytica	hypothetical protein	0.0002	0	0.5
Plasmodium falciparum	protoporphyrinogen oxidase	0.0051	0.1261	1
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1261	0.8358
Schistosoma mansoni	amine oxidase	0.0051	0.1261	0.1261
Brugia malayi	hypothetical protein	0.006	0.1509	1
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0051	0.1261	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	allatostatin A receptor	0.006	0.1509	0.1739
Mycobacterium leprae	PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO)	0.0384	1	0.5
Brugia malayi	SWIRM domain containing protein	0.0051	0.1261	0.8358
Mycobacterium ulcerans	protoporphyrinogen oxidase	0.0384	1	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis		0.0051	0.1261	0.1261
Echinococcus multilocularis	G protein coupled receptor 139	0.006	0.1509	0.1509
Schistosoma mansoni	amine GPCR	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Onchocerca volvulus		0.006	0.1509	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Echinococcus granulosus	biogenic amine 5HT receptor	0.006	0.1509	0.1739
Echinococcus granulosus	protoporphyrinogen oxidase	0.0333	0.8676	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Echinococcus multilocularis	g-protein coupled receptor	0.006	0.1509	0.1509
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0384	1	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	alpha 1A adrenergic receptor	0.006	0.1509	0.1739
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	hypothetical protein	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	g-protein coupled receptor	0.006	0.1509	0.1739
Onchocerca volvulus		0.006	0.1509	1
Brugia malayi	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	hypothetical protein	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Plasmodium vivax	protoporphyrinogen oxidase, putative	0.0051	0.1261	1
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.006	0.1509	0.1509
Echinococcus multilocularis	g protein coupled receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1261	0.8358
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Mycobacterium tuberculosis	Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO)	0.0333	0.8676	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	neuropeptide F-like receptor	0.006	0.1509	0.1509
Echinococcus granulosus	neuropeptide Y receptor	0.006	0.1509	0.1739
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0051	0.1261	0.1261
Schistosoma mansoni	opsin-like receptor	0.006	0.1509	0.1509
Echinococcus granulosus	g protein coupled receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.006	0.1509	0.1739
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1261	0.8358
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	amine oxidase	0.0051	0.1261	0.1261
Echinococcus granulosus	leucine rich repeat serine:threonine protein	0.0057	0.1429	0.1647
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.006	0.1509	1
Echinococcus multilocularis	neuropeptide Y receptor	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Onchocerca volvulus		0.006	0.1509	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Echinococcus granulosus	tachykinin peptides receptor 99D	0.006	0.1509	0.1739
Brugia malayi	RE15519p	0.006	0.1509	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.006	0.1509	0.1739
Echinococcus granulosus	fmrfamide receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	G-protein coupled receptor	0.006	0.1509	1
Brugia malayi	Tachykinin-like peptides receptor 99D	0.006	0.1509	1
Schistosoma mansoni	biogenic amine receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.006	0.1509	1
Echinococcus granulosus	neuropeptides capa receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.006	0.1509	1
Echinococcus granulosus	tm gpcr rhodopsin	0.006	0.1509	0.1739
Schistosoma mansoni	opsin-like receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	leucine rich repeat serine:threonine protein	0.0057	0.1419	0.1419
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Brugia malayi	hypothetical protein	0.0051	0.1261	0.8358
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	g protein coupled receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Onchocerca volvulus		0.006	0.1509	1
Schistosoma mansoni	opsin-like receptor	0.006	0.1509	0.1509
Echinococcus multilocularis	neuropeptides capa receptor	0.006	0.1509	0.1509
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.006	0.1509	0.1509
Echinococcus granulosus	neuropeptides capa receptor	0.006	0.1509	0.1739
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.006	0.1509	0.1509
Brugia malayi	putative neuropeptide receptor	0.006	0.1509	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.006	0.1509	0.1509
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.006	0.1509	1
Echinococcus multilocularis	orexin receptor type 2	0.006	0.1509	0.1509
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.006	0.1509	0.1509
Schistosoma mansoni	biogenic amine (5HT) receptor	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Echinococcus multilocularis	sex peptide receptor	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Echinococcus granulosus	orexin receptor type 2	0.006	0.1509	0.1739
Onchocerca volvulus		0.006	0.1509	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Echinococcus granulosus	g protein coupled receptor	0.006	0.1509	0.1739
Echinococcus granulosus	tm gpcr rhodopsin	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	neuropeptide FF receptor 2	0.006	0.1509	0.1509
Schistosoma mansoni	neuropeptide F-like receptor	0.006	0.1509	0.1509
Schistosoma mansoni	biogenic amine (5HT) receptor	0.006	0.1509	0.1509
Echinococcus granulosus	hypothetical protein	0.006	0.1509	0.1739
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Onchocerca volvulus		0.0051	0.1261	0.8358
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	neuropeptide F receptor	0.006	0.1509	1
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0051	0.1261	1
Onchocerca volvulus		0.006	0.1509	1
Echinococcus granulosus	g protein coupled receptor	0.006	0.1509	0.1739
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.006	0.1509	0.1509
Schistosoma mansoni	biogenic amine receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	G-protein coupled receptor	0.006	0.1509	1
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.006	0.1509	1
Brugia malayi	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Brugia malayi	Dopamine receptor protein 1	0.006	0.1509	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.006	0.1509	0.1509
Plasmodium vivax	lysine-specific histone demethylase 1, putative	0.0051	0.1261	1
Schistosoma mansoni	hypothetical protein	0.006	0.1509	0.1509
Brugia malayi	sulfakinin receptor protein	0.006	0.1509	1
Echinococcus granulosus	7tm_1 domain containing protein	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1261	0.8358
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0051	0.1261	0.1453
Plasmodium vivax	hypothetical protein, conserved	0.0051	0.1261	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.006	0.1509	0.1509
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.006	0.1509	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	neuropeptides capa receptor	0.006	0.1509	0.1509
Schistosoma mansoni	amine GPCR	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.006	0.1509	0.1509
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.006	0.1509	0.1509
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.006	0.1509	0.1509
Echinococcus multilocularis	serotonin receptor	0.006	0.1509	0.1509
Echinococcus granulosus	biogenic amine 5HT receptor	0.006	0.1509	0.1739
Trypanosoma brucei	Rab-like 5, small G protein	0.0002	0	0.5
Onchocerca volvulus		0.006	0.1509	1
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.006	0.1509	1
Trichomonas vaginalis	GTP binding protein rare7l, putative	0.0002	0	0.5
Echinococcus granulosus	G protein coupled receptor 139	0.006	0.1509	0.1739
Brugia malayi	Dopamine receptor	0.006	0.1509	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.006	0.1509	0.1509
Echinococcus multilocularis	neuropeptide receptor A26	0.006	0.1509	0.1509
Echinococcus granulosus	peptide allatostatin:somatostatin	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	serotonin receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	neuropeptide F receptor	0.006	0.1509	1
Brugia malayi	putative neuropeptide receptor NPR1	0.006	0.1509	1
Toxoplasma gondii	histone lysine-specific demethylase LSD1/BHC110/KDMA1A	0.0051	0.1261	0.5
Echinococcus multilocularis	fmrfamide receptor	0.006	0.1509	0.1509
Schistosoma mansoni	amine GPCR	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Toxoplasma gondii	histone lysine-specific demethylase	0.0051	0.1261	0.5
Plasmodium vivax	hypothetical protein, conserved	0.0051	0.1261	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.006	0.1509	0.1509
Echinococcus multilocularis	g protein coupled receptor	0.006	0.1509	0.1509
Echinococcus granulosus	somatostatin receptor	0.006	0.1509	0.1739
Loa Loa (eye worm)	melatonin receptor type 1A	0.006	0.1509	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.006	0.1509	1
Echinococcus granulosus	neuropeptide receptor A26	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus granulosus	neuropeptide Y receptor	0.006	0.1509	0.1739
Brugia malayi	amine oxidase, flavin-containing family protein	0.0051	0.1261	0.8358
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.006	0.1509	0.1739
Leishmania major	UDP-galactopyranose mutase	0.0051	0.1261	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Brugia malayi	Serotonin receptor	0.006	0.1509	1
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0384	1	1
Echinococcus multilocularis	neuropeptide receptor	0.006	0.1509	0.1509
Echinococcus granulosus	neuropeptide receptor	0.006	0.1509	0.1739
Brugia malayi	G-protein coupled receptor	0.006	0.1509	1
Schistosoma mansoni	neuropeptide receptor	0.006	0.1509	0.1509
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.006	0.1509	0.1509
Echinococcus granulosus	dro:myosuppressin receptor	0.006	0.1509	0.1739
Onchocerca volvulus		0.006	0.1509	1
Onchocerca volvulus		0.006	0.1509	1
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0051	0.1261	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.006	0.1509	0.1739
Brugia malayi	G protein-coupled receptor	0.006	0.1509	1
Brugia malayi	larval opioid receptor	0.006	0.1509	1
Schistosoma mansoni	growth hormone secretagogue receptor	0.006	0.1509	0.1509
Echinococcus granulosus	sex peptide receptor	0.006	0.1509	0.1739
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.006	0.1509	0.1509
Echinococcus granulosus	neuropeptide receptor	0.006	0.1509	0.1739
Schistosoma mansoni	neuropeptide f receptor 76f	0.006	0.1509	0.1509
Schistosoma mansoni	neuropeptide receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	serotonin receptor	0.006	0.1509	0.1509
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Brugia malayi	Dopamine receptor protein 2	0.006	0.1509	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.006	0.1509	0.1509
Echinococcus granulosus	rhodopsin orphan GPCR	0.006	0.1509	0.1739
Plasmodium falciparum	lysine-specific histone demethylase 1, putative	0.0051	0.1261	1
Schistosoma mansoni	amine GPCR	0.006	0.1509	0.1509
Schistosoma mansoni	alpha-1 adrenergic receptor	0.006	0.1509	0.1509
Echinococcus granulosus	7TM GPCR rhodopsin	0.006	0.1509	0.1739
Schistosoma mansoni	hypothetical protein	0.006	0.1509	0.1509
Echinococcus multilocularis	neuropeptide receptor	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.006	0.1509	0.1509
Trichomonas vaginalis	conserved hypothetical protein	0.0002	0	0.5
Echinococcus multilocularis	somatostatin receptor	0.006	0.1509	0.1509
Brugia malayi	ORL1-like opioid receptor	0.006	0.1509	1
Brugia malayi	neuropeptide F receptor	0.006	0.1509	1
Brugia malayi	neuropeptide F receptor	0.006	0.1509	1
Brugia malayi	follicle stimulating hormone receptor	0.006	0.1509	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.006	0.1509	0.1739
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1261	0.8358
Entamoeba histolytica	hypothetical protein	0.0002	0	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.006	0.1509	0.1509
Onchocerca volvulus		0.006	0.1509	1
Trichomonas vaginalis	hypothetical protein	0.0002	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Onchocerca volvulus		0.006	0.1509	1
Loa Loa (eye worm)	TYRA-2 protein	0.006	0.1509	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Brugia malayi	AKH receptor	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1261	0.8358
Schistosoma mansoni	biogenic amine receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Brugia malayi	G-protein coupled receptor	0.006	0.1509	1
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Brugia malayi	Melatonin receptor type 1A	0.006	0.1509	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1
Echinococcus multilocularis	neuropeptide s receptor	0.006	0.1509	0.1509
Brugia malayi	Protein kinase domain containing protein	0.0057	0.1419	0.9408
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.006	0.1509	0.1509
Echinococcus multilocularis	fmrfamide receptor	0.006	0.1509	0.1509
Brugia malayi	hypothetical protein	0.006	0.1509	1
Schistosoma mansoni	neuropeptide receptor	0.006	0.1509	0.1509
Schistosoma mansoni	neuropeptide receptor	0.006	0.1509	0.1509
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0051	0.1261	0.1261
Onchocerca volvulus	Neuropeptide F receptor homolog	0.006	0.1509	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.006	0.1509	0.1509
Loa Loa (eye worm)	hypothetical protein	0.006	0.1509	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2269197

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1841863