Detailed information for compound 1842279

Basic information

Technical information
  • TDR Targets ID: 1842279
  • Name: 1-methoxy-2-prop-2-enyl-4-propoxybenzene
  • MW: 206.281 | Formula: C13H18O2
  • H donors: 0 H acceptors: 0 LogP: 3.83 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCOc1ccc(c(c1)CC=C)OC
  • InChi: 1S/C13H18O2/c1-4-6-11-10-12(15-9-5-2)7-8-13(11)14-3/h4,7-8,10H,1,5-6,9H2,2-3H3
  • InChiKey: HRQYZNPNHWCOQG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-allyl-1-methoxy-4-propoxy-benzene
  • 2-allyl-1-methoxy-4-propoxybenzene
  • 1-methoxy-2-prop-2-enyl-4-propoxy-benzene

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0204 0.9996 0.9996
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0107 0.4729 0.4729
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0107 0.4729 0.9833
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0026 0.0264 0.0264
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.1786 0.3777
Brugia malayi MH2 domain containing protein 0.0078 0.3153 0.6557
Loa Loa (eye worm) hypothetical protein 0.0039 0.1001 0.1001
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0109 0.4809 1
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0109 0.4809 0.4809
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0026 0.0264 0.0264
Echinococcus multilocularis lysosomal alpha glucosidase 0.0093 0.396 0.396
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0109 0.4809 1
Entamoeba histolytica protein kinase domain containing protein 0.0109 0.4809 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0107 0.4729 1
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Trypanosoma brucei polo-like protein kinase 0.0107 0.4729 0.9833
Schistosoma mansoni hypothetical protein 0.0204 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4759 0.4759
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.1786 0.3777
Echinococcus granulosus dual specificity 0.0109 0.4809 0.4809
Loa Loa (eye worm) MH2 domain-containing protein 0.0078 0.3153 0.3153
Echinococcus granulosus lysosomal alpha glucosidase 0.0093 0.396 0.396
Schistosoma mansoni calcium-activated potassium channel 0.0204 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Loa Loa (eye worm) transcription factor SMAD2 0.0078 0.3153 0.3153
Entamoeba histolytica protein kinase, putative 0.0109 0.4809 1
Entamoeba histolytica protein kinase, putative 0.0109 0.4809 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0093 0.396 0.396
Schistosoma mansoni alpha-glucosidase 0.008 0.3251 0.3251
Loa Loa (eye worm) hypothetical protein 0.0108 0.4759 0.4759
Loa Loa (eye worm) hypothetical protein 0.0204 1 1
Echinococcus multilocularis geminin 0.0204 0.9996 0.9996
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.4729 0.4729
Echinococcus granulosus geminin 0.0204 0.9996 0.9996
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0026 0.0264 0.0548
Brugia malayi serine/threonine-protein kinase plk-2 0.0107 0.4729 0.9833
Trypanosoma cruzi polo-like protein kinase, putative 0.0107 0.4729 0.9833
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0026 0.0264 0.0264
Brugia malayi Protein kinase domain containing protein 0.0109 0.4809 1
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0093 0.396 0.8235
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Schistosoma mansoni alpha-glucosidase 0.008 0.3251 0.3251
Loa Loa (eye worm) hypothetical protein 0.0074 0.2919 0.2919
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0109 0.4809 1
Schistosoma mansoni calcium-activated potassium channel 0.0157 0.7431 0.7431
Entamoeba histolytica hypothetical protein 0.0109 0.4809 1
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0093 0.396 0.396
Schistosoma mansoni kinase 0.0055 0.1863 0.1863
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0026 0.0264 0.0264
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0026 0.0264 0.0264
Giardia lamblia Kinase, PLK 0.0107 0.4729 0.5
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0107 0.4729 0.9833
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0021 0 0.5
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0107 0.4729 0.4729
Entamoeba histolytica serine/threonine protein kinase, putative 0.0107 0.4729 0.9833
Loa Loa (eye worm) hypothetical protein 0.0083 0.3382 0.3382
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0026 0.0264 0.0264
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0026 0.0264 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.4809 0.4809
Echinococcus multilocularis dual specificity 0.0109 0.4809 0.4809
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0026 0.0264 0.0264
Schistosoma mansoni hypothetical protein 0.0204 0.9996 0.9996
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.4729 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0107 0.4729 0.4729
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0109 0.4809 1
Echinococcus multilocularis small conductance calcium activated potassium 0.0204 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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