Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0355 | 0.177 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0336 | 0.1569 | 0.2238 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0355 | 0.177 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0355 | 0.177 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0355 | 0.177 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0355 | 0.177 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0355 | 0.177 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0534 | 0.3667 | 0.5951 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.1133 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0355 | 0.177 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0355 | 0.177 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Brugia malayi | steroid hormone receptor | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0355 | 0.177 | 1 |
Onchocerca volvulus | 0.0355 | 0.177 | 0.5 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0355 | 0.177 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0355 | 0.177 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0355 | 0.177 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0355 | 0.177 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0383 | 0.2063 | 0.3111 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0355 | 0.177 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0355 | 0.177 | 1 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0383 | 0.2063 | 0.5229 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0355 | 0.177 | 1 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0534 | 0.3667 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0355 | 0.177 | 1 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.1133 | 1 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0355 | 0.177 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0383 | 0.2063 | 0.3111 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0355 | 0.177 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0355 | 0.177 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0355 | 0.177 | 1 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0751 | 0.5955 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0534 | 0.3667 | 0.5951 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0355 | 0.177 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0355 | 0.177 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0355 | 0.177 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0355 | 0.177 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.