Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0187 | 0.1686 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0171 | 0.1349 | 0.5 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0193 | 0.1813 | 0.3111 |
Schistosoma mansoni | nephrin | 0.0171 | 0.1349 | 0.5 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0193 | 0.1813 | 0.3111 |
Echinococcus granulosus | defective proboscis extension response | 0.0171 | 0.1349 | 0.5 |
Echinococcus multilocularis | Immunoglobulin | 0.0171 | 0.1349 | 0.5 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0378 | 0.5827 | 1 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0171 | 0.1349 | 0.5 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0171 | 0.1349 | 0.5 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0269 | 0.3468 | 0.5951 |
Echinococcus multilocularis | Immunoglobulin | 0.0171 | 0.1349 | 0.5 |
Schistosoma mansoni | cell adhesion molecule | 0.0171 | 0.1349 | 0.5 |
Echinococcus granulosus | Immunoglobulin | 0.0171 | 0.1349 | 0.5 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0571 | 1 | 0.5 |
Echinococcus granulosus | neuroglian | 0.0171 | 0.1349 | 0.5 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0193 | 0.1813 | 0.5229 |
Schistosoma mansoni | vesicular amine transporter | 0.0171 | 0.1349 | 0.5 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0171 | 0.1349 | 0.5 |
Echinococcus multilocularis | roundabout 2 | 0.0171 | 0.1349 | 0.5 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0571 | 1 | 0.5 |
Echinococcus granulosus | twitchin | 0.0171 | 0.1349 | 0.5 |
Echinococcus multilocularis | neuroglian | 0.0171 | 0.1349 | 0.5 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0269 | 0.3468 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0269 | 0.3468 | 0.5951 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0169 | 0.1304 | 0.2238 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0187 | 0.1686 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0171 | 0.1349 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.