Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0385 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin family protein | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | Mastin | 0.0385 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0385 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0267 | 0.5157 | 0.5157 |
Mycobacterium ulcerans | hypothetical protein | 0.0385 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0267 | 0.5157 | 0.5157 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | hypothetical protein | 0.0385 | 1 | 1 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0267 | 0.5157 | 0.5157 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0267 | 0.5157 | 0.5157 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | thyroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0385 | 1 | 1 |
Echinococcus multilocularis | Mastin | 0.0385 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin family protein | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | steroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | coup transcription factor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | hypothetical protein | 0.0385 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0385 | 1 | 1 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin family protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | enteropeptidase | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | enteropeptidase | 0.0385 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | trypsin family protein | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.