Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0385 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Echinococcus multilocularis | FTZ F1 alpha | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin family protein | 0.0385 | 1 | 1 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | thyroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin family protein | 0.0385 | 1 | 1 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0385 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0385 | 1 | 1 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus multilocularis | enteropeptidase | 0.0385 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0385 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | steroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0267 | 0.5157 | 0.5157 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | nuclear receptor NHR-88 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus granulosus | Mastin | 0.0385 | 1 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | Mastin | 0.0385 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0267 | 0.5157 | 0.5157 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | hypothetical protein | 0.0385 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0385 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | enteropeptidase | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | ecdysteroid receptor | 0.0267 | 0.5157 | 0.5157 |
Onchocerca volvulus | 0.0385 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | trypsin family protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin family protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | coup transcription factor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0267 | 0.5157 | 0.5157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0267 | 0.5157 | 0.5157 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0267 | 0.5157 | 0.5157 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0385 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0385 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0385 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0267 | 0.5157 | 0.5157 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0267 | 0.5157 | 0.5157 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.