Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | glycylpeptide N-tetradecanoyltransferase | 0.0176 | 0.7107 | 0.5 |
Brugia malayi | N-myristoyltransferase 2 | 0.0176 | 0.7107 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0 | 0.5 |
Onchocerca volvulus | 0.0037 | 0 | 0.5 | |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0 | 0.5 |
Loa Loa (eye worm) | N-myristoyltransferase 2 | 0.0176 | 0.7107 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0 | 0.5 |
Entamoeba histolytica | glycylpeptide N-tetradecanoyltransferase, putative | 0.0176 | 0.7107 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0 | 0.5 |
Trichomonas vaginalis | N-myristoyl transferase, putative | 0.0176 | 0.7107 | 1 |
Onchocerca volvulus | 0.0037 | 0 | 0.5 | |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0 | 0.5 |
Leishmania major | N-myristoyl transferase, putative | 0.0176 | 0.7107 | 1 |
Trypanosoma brucei | N-myristoyltransferase | 0.0176 | 0.7107 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0 | 0.5 |
Plasmodium vivax | glycylpeptide N-tetradecanoyltransferase, putative | 0.0176 | 0.7107 | 1 |
Trypanosoma cruzi | N-myristoyl transferase, putative | 0.0176 | 0.7107 | 1 |
Trypanosoma cruzi | N-myristoyl transferase, putative | 0.0176 | 0.7107 | 1 |
Schistosoma mansoni | N-myristoyltransferase | 0.0176 | 0.7107 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0 | 0.5 |
Trichomonas vaginalis | N-myristoyl transferase, putative | 0.0116 | 0.4033 | 0.5675 |
Giardia lamblia | CDC72 | 0.0176 | 0.7107 | 0.5 |
Trypanosoma brucei | N-myristoyl transferase, putative | 0.0176 | 0.7107 | 1 |
Echinococcus granulosus | glycylpeptide N tetradecanoyltransferase | 0.0176 | 0.7107 | 1 |
Onchocerca volvulus | 0.0037 | 0 | 0.5 | |
Echinococcus multilocularis | glycylpeptide N tetradecanoyltransferase | 0.0176 | 0.7107 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.